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crb3 rixosome complex WD repeat subunit Crb3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542844, updated on 18-Sep-2024

Summary

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Official Symbol
crb3
Official Full Name
rixosome complex WD repeat subunit Crb3
Primary source
PomBase:SPAC13G7.08c
Locus tag
SPOM_SPAC13G7.08C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
ipi3
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Genomic context

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See crb3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (2310271..2311928, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phosphoadenosine phosphosulfate reductase Neighboring gene ncRNA Neighboring gene argonaute binding protein 2 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Myb family telomere binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing. Kitano E, et al. J Biol Chem, 2011 Apr 29. PMID 21385875, Free PMC Article
  2. Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1. Saka Y, et al. Genes Dev, 1997 Dec 15. PMID 9407031, Free PMC Article
  3. Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication. Taricani L, et al. Mol Biol Cell, 2006 Aug. PMID 16723501, Free PMC Article
  4. A large complex mediated by Moc1, Moc2 and Cpc2 regulates sexual differentiation in fission yeast. Paul SK, et al. FEBS J, 2009 Sep. PMID 19682301
  5. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cell division site HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in heterochromatin IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pre-replicative complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of rixosome complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of rixosome complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
rixosome complex WD repeat subunit Crb3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2310271..2311928 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019141.3 → NP_593710.1  rixosome complex WD repeat subunit Crb3 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_593710.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q10272
    Conserved Domains (4) summary
    COG2319
    Location:67 → 358
    WD40; WD40 repeat [General function prediction only]
    pfam16858
    Location:45 → 71
    CNDH2_C; Condensin II complex subunit CAP-H2 or CNDH2, C-term
    sd00039
    Location:81 → 116
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:81 → 355
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
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