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Ccdc124 coiled-coil domain containing 124 [ Mus musculus (house mouse) ]

Gene ID: 234388, updated on 27-Nov-2024

Summary

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Official Symbol
Ccdc124provided by MGI
Official Full Name
coiled-coil domain containing 124provided by MGI
Primary source
MGI:MGI:1916403
See related
Ensembl:ENSMUSG00000007721 AllianceGenome:MGI:1916403
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1810023B24Rik
Summary
Predicted to enable transcription coactivator activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Orthologous to human CCDC124 (coiled-coil domain containing 124). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 50.0), frontal lobe adult (RPKM 46.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc124 in Genome Data Viewer
Location:
8 B3.3; 8 34.33 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (71320870..71326134, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70868226..70873490, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E133 Neighboring gene arrestin domain containing 2 Neighboring gene potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 Neighboring gene STARR-positive B cell enhancer ABC_E3780 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:73389712-73389895 Neighboring gene STARR-positive B cell enhancer ABC_E8242 Neighboring gene STARR-seq mESC enhancer starr_21801 Neighboring gene solute carrier family 5 (sodium iodide symporter), member 5 Neighboring gene ribosomal protein L18A Neighboring gene microRNA 7067

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins. Lang B, et al. Nucleic Acids Res, 2021 Jul 9. PMID 34133714, Free PMC Article
  2. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
  3. ATG5 is required for B cell polarization and presentation of particulate antigens. Arbogast F, et al. Autophagy, 2019 Feb. PMID 30196744, Free PMC Article
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in midbody IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 124

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026964.3 → NP_081240.1  coiled-coil domain-containing protein 124

    See identical proteins and their annotated locations for NP_081240.1

    Status: PROVISIONAL

    Source sequence(s)
    AC019302
    Consensus CDS
    CCDS22384.1
    UniProtKB/Swiss-Prot
    Q8C2T0, Q9D8X2
    Related
    ENSMUSP00000007865.6, ENSMUST00000007865.7
    Conserved Domains (1) summary
    pfam06244
    Location:95 → 206
    Ccdc124; Coiled-coil domain-containing protein 124

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    71320870..71326134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036153949.1 → XP_036009842.1  coiled-coil domain-containing protein 124 isoform X1

    UniProtKB/Swiss-Prot
    Q8C2T0, Q9D8X2
    Conserved Domains (1) summary
    pfam06244
    Location:95 → 206
    Ccdc124; Coiled-coil domain-containing protein 124

  2. XM_006509655.4 → XP_006509718.1  coiled-coil domain-containing protein 124 isoform X1

    See identical proteins and their annotated locations for XP_006509718.1

    UniProtKB/Swiss-Prot
    Q8C2T0, Q9D8X2
    Conserved Domains (1) summary
    pfam06244
    Location:95 → 206
    Ccdc124; Coiled-coil domain-containing protein 124
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D8X2.1 GenPept UniProtKB/Swiss-Prot:Q9D8X2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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