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tre-4 Trehalase [ Caenorhabditis elegans ]

Gene ID: 184505, updated on 9-Dec-2024

Summary

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Official Symbol
tre-4
Official Full Name
Trehalase
Primary source
WormBase:WBGene00006610
Locus tag
CELE_F15A2.2
See related
AllianceGenome:WB:WBGene00006610
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable alpha,alpha-trehalase activity. Predicted to be involved in trehalose catabolic process. Predicted to be located in membrane. Is expressed in several structures, including excretory cell; intestine; nervous system; pharynx; and reproductive system. Orthologous to human TREH (trehalase). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See tre-4 in Genome Data Viewer
Location:
chromosome: X
Exon count:
11
Sequence:
Chromosome: X; NC_003284.9 (13472155..13475926)

Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Ephrin RBD domain-containing protein Neighboring gene Serpentine receptor class delta-50 Neighboring gene Serpentine receptor class delta-51 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Trehalose metabolism genes in Caenorhabditis elegans and filarial nematodes. Pellerone FI, et al. Int J Parasitol, 2003 Sep 30. PMID 13678635
  2. C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens. Ju S, et al. Commun Biol, 2022 Jun 30. PMID 35773333, Free PMC Article
  3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables alpha,alpha-trehalase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha,alpha-trehalase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in trehalose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in trehalose metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Trehalase
NP_510249.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003284.9 Reference assembly

    Range
    13472155..13475926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_077848.9 → NP_510249.2  Trehalase [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_510249.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    G5EDP3
    Conserved Domains (1) summary
    cl17346
    Location:80 → 557
    Trehalase; Trehalase
Nucleotide Protein
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