NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|71987755|ref|NP_510249|]
View 

Trehalase [Caenorhabditis elegans]

Protein Classification

trehalase domain-containing protein( domain architecture ID 108014)

trehalase domain-containing protein may catalyze the hydrolysis of alpha,alpha-trehalose to form alpha- and beta-D-glucose

CAZY:  GH37
EC:  3.2.1.28
Gene Ontology:  GO:0004555|GO:0005991

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Trehalase super family cl17346
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 80-557 6.72e-118

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


The actual alignment was detected with superfamily member PLN02567:

Pssm-ID: 418443  Cd Length: 554  Bit Score: 362.43  E-value: 6.72e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   80 LKVTAKEVLANFNKLP-----WPLKKEVFQQFCEEHFEQV-NYLEVVNLTDYEVQPK-FLNEIGNLSHRKLAAEMHERWE 152
Cdd:PLN02567  38 LKFSLSETEKAFDALPrsninGSVPVEELEEFVAEYFDVAgSDLLPYTPPDFVPEPPgFLPKVENPEAREWALKVHSLWK 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  153 RLARQFTSDVQHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNL 232
Cdd:PLN02567 118 NLARKVSDSVEERPDRHTLLPLPNPVVVPGSRFREVYYWDSYWVIRGLLASKMYETAKGVVENLLYLVDTYGFVPNGARA 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  233 QLSRRSQPPLFPHMIWEYTKATGNYE--KQWIDSMDMEMKFW-ENNRTIAIG-----THKLFLYKTLTNCPRPENFLGDF 304
Cdd:PLN02567 198 YYTNRSQPPLLSAMVLAVYAATKDVElvRRALPALLKEHAFWtSGRHTVTIRdangvVHVLSRYYAMWDKPRPESSRIDK 277

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  305 NIGKAAKTPSD---VWRSISSACESGWDFSSRWMHNNDtDLSSIHTDLIIPVDLNVFIannYRY---MAYYANHFG---- 374
Cdd:PLN02567 278 EVASKFSSSSEkqqLYRDIASAAESGWDFSSRWMRDGS-NLTTLRTTSILPVDLNAFL---LKMeldIAFFAKLLGdkat 353

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  375 --RFDKSASYRQKyeklryAIQEVLWDNNLGAWFDY-----DISIQKR--------NLNFYPSNVYPLMLEGMDKFADRV 439
Cdd:PLN02567 354 aeRFLKAAKARKR------AINAVLWNEEMGQWLDYwlppnGATCQESytwdaenqNTNVYASNFVPLWCGVVPPGDAKV 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  440 EDYM---KKSGaLEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFMACNNSFLQQEAKKQAMEFIETVYNGMYNpia 516
Cdd:PLN02567 428 EKVVeslKSSG-LVLPAGIATSL-RNTGQQWDFPNAWAPLQHMIVEGLAASGSKEGKALAEDIARRWLRSNYVAYKK--- 502

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 71987755  517 glDGGVWEKYDARSTnGAPGAGGEYVVQEGFGWTNGAVMDL 557
Cdd:PLN02567 503 --TGAMHEKYDARYC-GEVGGGGEYIPQTGFGWSNGVVLSL 540
 
Name Accession Description Interval E-value
PLN02567 PLN02567
alpha,alpha-trehalase
 80-557 6.72e-118

alpha,alpha-trehalase


Pssm-ID: 215307  Cd Length: 554  Bit Score: 362.43  E-value: 6.72e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   80 LKVTAKEVLANFNKLP-----WPLKKEVFQQFCEEHFEQV-NYLEVVNLTDYEVQPK-FLNEIGNLSHRKLAAEMHERWE 152
Cdd:PLN02567  38 LKFSLSETEKAFDALPrsninGSVPVEELEEFVAEYFDVAgSDLLPYTPPDFVPEPPgFLPKVENPEAREWALKVHSLWK 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  153 RLARQFTSDVQHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNL 232
Cdd:PLN02567 118 NLARKVSDSVEERPDRHTLLPLPNPVVVPGSRFREVYYWDSYWVIRGLLASKMYETAKGVVENLLYLVDTYGFVPNGARA 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  233 QLSRRSQPPLFPHMIWEYTKATGNYE--KQWIDSMDMEMKFW-ENNRTIAIG-----THKLFLYKTLTNCPRPENFLGDF 304
Cdd:PLN02567 198 YYTNRSQPPLLSAMVLAVYAATKDVElvRRALPALLKEHAFWtSGRHTVTIRdangvVHVLSRYYAMWDKPRPESSRIDK 277

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  305 NIGKAAKTPSD---VWRSISSACESGWDFSSRWMHNNDtDLSSIHTDLIIPVDLNVFIannYRY---MAYYANHFG---- 374
Cdd:PLN02567 278 EVASKFSSSSEkqqLYRDIASAAESGWDFSSRWMRDGS-NLTTLRTTSILPVDLNAFL---LKMeldIAFFAKLLGdkat 353

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  375 --RFDKSASYRQKyeklryAIQEVLWDNNLGAWFDY-----DISIQKR--------NLNFYPSNVYPLMLEGMDKFADRV 439
Cdd:PLN02567 354 aeRFLKAAKARKR------AINAVLWNEEMGQWLDYwlppnGATCQESytwdaenqNTNVYASNFVPLWCGVVPPGDAKV 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  440 EDYM---KKSGaLEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFMACNNSFLQQEAKKQAMEFIETVYNGMYNpia 516
Cdd:PLN02567 428 EKVVeslKSSG-LVLPAGIATSL-RNTGQQWDFPNAWAPLQHMIVEGLAASGSKEGKALAEDIARRWLRSNYVAYKK--- 502

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 71987755  517 glDGGVWEKYDARSTnGAPGAGGEYVVQEGFGWTNGAVMDL 557
Cdd:PLN02567 503 --TGAMHEKYDARYC-GEVGGGGEYIPQTGFGWSNGVVLSL 540
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 69-558 4.66e-117

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 358.57  E-value: 4.66e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755    69 FGLQKTCPGDKLKVTAKEVLANFNKLPW-----PLKKEVFQQFCEEHF-EQVNYLEVVNLTDYEVQPKFLNEIGNLSHRK 142
Cdd:pfam01204   3 FPDQKTFVDEARLNEPNRILRLIRAQFWraltrRIDGEDLRAFVEDYFdEPGDELPRIVPYDEKEQPEFLQKIEDPDLRL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   143 LAAEMHERWERLARQFTSDVQHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVT 222
Cdd:pfam01204  83 WVEELNALWPALVRKINKKPGLLPEASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLIET 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   223 LGYIPNSGNLQLSRRSQPPLFPHMIWEYTKATGNYE--KQWIDSMDMEMKFW-ENNRTIAI----GTHKLFLYKTLTNCP 295
Cdd:pfam01204 163 YGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKTEDDAllRRYLAALKKEYAFWmANPRLDPVtglsDGYLLNRYGVPPETP 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   296 RPENFLGDFNIGKAAKT---PSDVWRSISSACESGWDFSSRWMHN--NDTDLSSIHTDLIIPVDLNVFIANNYRYMAYYA 370
Cdd:pfam01204 243 RPESYLEDVEYAEKLPKerpKAYNYRDLKAGAESGWDFSSRWVREghDTGYLAEIRTTSLVPVDLNALLYKYEKDIAFFC 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   371 NHFGRFDKSASYRQKYEKLRYAIQEVLWDNNLGAWFDYDISIQKRNLNFYPSNVYPLML----EGMDKFADRVEDYMKKS 446
Cdd:pfam01204 323 DVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAglasPDQAKMVAKVLPKLEES 402

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   447 GALEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFmacNNSFLQQEAKKQAMEFIETVYNGMYNpiaglDGGVWEKY 526
Cdd:pfam01204 403 GLLVFPGGRPTSL-LDSGQQWDYPNGWAPLQWLAVEGL---QRYGYDELAERLAYRWLFTNTKAFVD-----EGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|..
gi 71987755   527 DARSTNGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:pfam01204 474 DVTRGGEYGGGGGEYVPQEGFGWTNGVYLYFL 505
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
148-558 4.49e-87

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 278.27  E-value: 4.49e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 148 HERWERLARQFTSDVQHHPdlypLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIP 227
Cdd:COG1626  23 DALWPVLTRTPDEPNEGSS----LLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLARDMVDNFAYLIDRYGHIP 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 228 NsGNLQ--LSrRSQPPLFPHMIWEYTKATGN--YEKqWIDSMDMEMKFW-ENNRTIAIGTHKLFLYKTLTNC-------- 294
Cdd:COG1626  99 N-GNRTyyLS-RSQPPFFALMVELLAEHTGDewLRR-YLPQLEKEYAFWmDGADSLAPGQAYRRVVRLPDGTvlnrywdd 175

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 295 ---PRPENFLGDFNIGKAAKT--PSDVWRSISSACESGWDFSSRWMHNNDtDLSSIHTDLIIPVDLNVFIANNYRYMAYY 369
Cdd:COG1626 176 rdtPRPESYREDVETAKQSPErpAEEVYRDLRAGAESGWDFSSRWLADGK-DLATIRTTDIVPVDLNALLYHLETTLAKA 254

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 370 ANHFGRFDKSASYRQKYEKLRYAIQEVLWDNNLGAWFDYDISIQKRNLNFYPSNVYPLMLeGM--DKFADRVEDYMKKSg 447
Cdd:COG1626 255 YALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFA-GIatPEQAARVAETLEPQ- 332

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 448 aLEFVGGIPSSLPAqSTQQWDFPNVWAPNQHFVIQSFMACNNsflQQEAKKQA---MEFIETVYNgmynpiagLDGGVWE 524
Cdd:COG1626 333 -LLKPGGLVTTLVN-SGQQWDAPNGWAPLQWMAVKGLRNYGY---DDLAREIArrwLALVERVYE--------RTGKLVE 399

                       410       420       430
                ....*....|....*....|....*....|....
gi 71987755 525 KYDARSTnGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:COG1626 400 KYNVVDP-SLEAGGGEYPLQDGFGWTNGVYLALL 432
 
Name Accession Description Interval E-value
PLN02567 PLN02567
alpha,alpha-trehalase
 80-557 6.72e-118

alpha,alpha-trehalase


Pssm-ID: 215307  Cd Length: 554  Bit Score: 362.43  E-value: 6.72e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   80 LKVTAKEVLANFNKLP-----WPLKKEVFQQFCEEHFEQV-NYLEVVNLTDYEVQPK-FLNEIGNLSHRKLAAEMHERWE 152
Cdd:PLN02567  38 LKFSLSETEKAFDALPrsninGSVPVEELEEFVAEYFDVAgSDLLPYTPPDFVPEPPgFLPKVENPEAREWALKVHSLWK 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  153 RLARQFTSDVQHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNL 232
Cdd:PLN02567 118 NLARKVSDSVEERPDRHTLLPLPNPVVVPGSRFREVYYWDSYWVIRGLLASKMYETAKGVVENLLYLVDTYGFVPNGARA 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  233 QLSRRSQPPLFPHMIWEYTKATGNYE--KQWIDSMDMEMKFW-ENNRTIAIG-----THKLFLYKTLTNCPRPENFLGDF 304
Cdd:PLN02567 198 YYTNRSQPPLLSAMVLAVYAATKDVElvRRALPALLKEHAFWtSGRHTVTIRdangvVHVLSRYYAMWDKPRPESSRIDK 277

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  305 NIGKAAKTPSD---VWRSISSACESGWDFSSRWMHNNDtDLSSIHTDLIIPVDLNVFIannYRY---MAYYANHFG---- 374
Cdd:PLN02567 278 EVASKFSSSSEkqqLYRDIASAAESGWDFSSRWMRDGS-NLTTLRTTSILPVDLNAFL---LKMeldIAFFAKLLGdkat 353

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  375 --RFDKSASYRQKyeklryAIQEVLWDNNLGAWFDY-----DISIQKR--------NLNFYPSNVYPLMLEGMDKFADRV 439
Cdd:PLN02567 354 aeRFLKAAKARKR------AINAVLWNEEMGQWLDYwlppnGATCQESytwdaenqNTNVYASNFVPLWCGVVPPGDAKV 427

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  440 EDYM---KKSGaLEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFMACNNSFLQQEAKKQAMEFIETVYNGMYNpia 516
Cdd:PLN02567 428 EKVVeslKSSG-LVLPAGIATSL-RNTGQQWDFPNAWAPLQHMIVEGLAASGSKEGKALAEDIARRWLRSNYVAYKK--- 502

                        490       500       510       520
                 ....*....|....*....|....*....|....*....|.
gi 71987755  517 glDGGVWEKYDARSTnGAPGAGGEYVVQEGFGWTNGAVMDL 557
Cdd:PLN02567 503 --TGAMHEKYDARYC-GEVGGGGEYIPQTGFGWSNGVVLSL 540
Trehalase pfam01204
Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a ...
 69-558 4.66e-117

Trehalase; Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.


Pssm-ID: 395961 [Multi-domain]  Cd Length: 509  Bit Score: 358.57  E-value: 4.66e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755    69 FGLQKTCPGDKLKVTAKEVLANFNKLPW-----PLKKEVFQQFCEEHF-EQVNYLEVVNLTDYEVQPKFLNEIGNLSHRK 142
Cdd:pfam01204   3 FPDQKTFVDEARLNEPNRILRLIRAQFWraltrRIDGEDLRAFVEDYFdEPGDELPRIVPYDEKEQPEFLQKIEDPDLRL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   143 LAAEMHERWERLARQFTSDVQHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVT 222
Cdd:pfam01204  83 WVEELNALWPALVRKINKKPGLLPEASSLLPLPNPFVVPGGRFRELYYWDSYFTILGLLESGMHDLAKGMVENFIYLIET 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   223 LGYIPNSGNLQLSRRSQPPLFPHMIWEYTKATGNYE--KQWIDSMDMEMKFW-ENNRTIAI----GTHKLFLYKTLTNCP 295
Cdd:pfam01204 163 YGHIPNGNRSYYLNRSQPPFLTDMVLLVYEKTEDDAllRRYLAALKKEYAFWmANPRLDPVtglsDGYLLNRYGVPPETP 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   296 RPENFLGDFNIGKAAKT---PSDVWRSISSACESGWDFSSRWMHN--NDTDLSSIHTDLIIPVDLNVFIANNYRYMAYYA 370
Cdd:pfam01204 243 RPESYLEDVEYAEKLPKerpKAYNYRDLKAGAESGWDFSSRWVREghDTGYLAEIRTTSLVPVDLNALLYKYEKDIAFFC 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   371 NHFGRFDKSASYRQKYEKLRYAIQEVLWDNNLGAWFDYDISIQKRNLNFYPSNVYPLML----EGMDKFADRVEDYMKKS 446
Cdd:pfam01204 323 DVLGDSETSAIWEERAEQRRLAIDKYLWNEEAGVWFDYDLKKRKQTNYFSATNFWPLWAglasPDQAKMVAKVLPKLEES 402

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755   447 GALEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFmacNNSFLQQEAKKQAMEFIETVYNGMYNpiaglDGGVWEKY 526
Cdd:pfam01204 403 GLLVFPGGRPTSL-LDSGQQWDYPNGWAPLQWLAVEGL---QRYGYDELAERLAYRWLFTNTKAFVD-----EGKMVEKY 473

                         490       500       510
                  ....*....|....*....|....*....|..
gi 71987755   527 DARSTNGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:pfam01204 474 DVTRGGEYGGGGGEYVPQEGFGWTNGVYLYFL 505
TreA COG1626
Neutral trehalase [Carbohydrate transport and metabolism];
148-558 4.49e-87

Neutral trehalase [Carbohydrate transport and metabolism];


Pssm-ID: 441233  Cd Length: 438  Bit Score: 278.27  E-value: 4.49e-87
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 148 HERWERLARQFTSDVQHHPdlypLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIP 227
Cdd:COG1626  23 DALWPVLTRTPDEPNEGSS----LLPLPHPYVVPGGRFREIYYWDSYFTMLGLAESGRWDLARDMVDNFAYLIDRYGHIP 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 228 NsGNLQ--LSrRSQPPLFPHMIWEYTKATGN--YEKqWIDSMDMEMKFW-ENNRTIAIGTHKLFLYKTLTNC-------- 294
Cdd:COG1626  99 N-GNRTyyLS-RSQPPFFALMVELLAEHTGDewLRR-YLPQLEKEYAFWmDGADSLAPGQAYRRVVRLPDGTvlnrywdd 175

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 295 ---PRPENFLGDFNIGKAAKT--PSDVWRSISSACESGWDFSSRWMHNNDtDLSSIHTDLIIPVDLNVFIANNYRYMAYY 369
Cdd:COG1626 176 rdtPRPESYREDVETAKQSPErpAEEVYRDLRAGAESGWDFSSRWLADGK-DLATIRTTDIVPVDLNALLYHLETTLAKA 254

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 370 ANHFGRFDKSASYRQKYEKLRYAIQEVLWDNNLGAWFDYDISIQKRNLNFYPSNVYPLMLeGM--DKFADRVEDYMKKSg 447
Cdd:COG1626 255 YALAGDPAKAAEYRARAERRKEAINRYLWDEERGFYFDYDFVTGKQTAVLSAAAFYPLFA-GIatPEQAARVAETLEPQ- 332

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 448 aLEFVGGIPSSLPAqSTQQWDFPNVWAPNQHFVIQSFMACNNsflQQEAKKQA---MEFIETVYNgmynpiagLDGGVWE 524
Cdd:COG1626 333 -LLKPGGLVTTLVN-SGQQWDAPNGWAPLQWMAVKGLRNYGY---DDLAREIArrwLALVERVYE--------RTGKLVE 399

                       410       420       430
                ....*....|....*....|....*....|....
gi 71987755 525 KYDARSTnGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:COG1626 400 KYNVVDP-SLEAGGGEYPLQDGFGWTNGVYLALL 432
treF PRK13270
alpha,alpha-trehalase TreF;
105-558 2.90e-59

alpha,alpha-trehalase TreF;


Pssm-ID: 183934  Cd Length: 549  Bit Score: 207.74  E-value: 2.90e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  105 QFCEEHFeqvnYLEVVNLTDYEVQP-KFLNE-IGNLshrklaaemherWERLARQftsdVQHHPDLYPLIPVQNPFIVPG 182
Cdd:PRK13270 107 KFVENHF----WLPEVYSSEYVSDPqNSLKEhIDQL------------WPVLTRE----PQDHIPWSSLLALPQSYIVPG 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  183 GRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNLQLSRRSQPPLFPHMIWEYTKATGNYEKQWI 262
Cdd:PRK13270 167 GRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVRGARRYL 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  263 DSMDMEMKFW-ENNRTIAIGT---HKLFL--------YKTLTNCPRPENFLGDFNIGKAAKTP-SDVWRSISSACESGWD 329
Cdd:PRK13270 247 DHLKMEYAFWmDGAESLIPNQayrHVVRMpdgsllnrYWDDRDTPRDESWLEDVETAKHSGRPpNEVYRDLRAGAASGWD 326

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  330 FSSRWMhNNDTDLSSIHTDLIIPVDLNVFIANNYRYMAYYANHFGRFDKSASYRQKYEKLRYAIQEVLWDNNLGAWFDYD 409
Cdd:PRK13270 327 YSSRWL-RDTGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGIYRDYD 405

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  410 ISIQKRNLnFYPSNVYPLMLeGMDKF--ADRVEDYMKKSgaLEFVGGIPSSLpAQSTQQWDFPNVWAPNQHFVIQSFMAC 487
Cdd:PRK13270 406 WRREQLAL-FSAAAIVPLYV-GMANHeqADRLANAVRSR--LLTPGGILASE-YETGEQWDKPNGWAPLQWMAIQGFKMY 480

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71987755  488 NNSFLQQEAKKQAMEFIETVYNGMYNPIagldggvwEKYDARSTNGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:PRK13270 481 GDDLLGDEIARSWLKTVNQFYQEHHKLI--------EKYHIAGGVPREGGGGEYPLQDGFGWTNGVVRRLI 543
treA PRK13272
alpha,alpha-trehalase TreA;
143-558 1.89e-58

alpha,alpha-trehalase TreA;


Pssm-ID: 183936  Cd Length: 542  Bit Score: 205.53  E-value: 1.89e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  143 LAAEMHERWERLARQFTsdvqHHPDLYPLIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVT 222
Cdd:PRK13272 120 LREHIDALWPKLVRSQE----QVPAHSSLLALPHPYVVPGGRFREVYYWDSYFTMLGLVKSGQTTLSRQMLDNFAYLIDT 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  223 LGYIPNSGNLQLSRRSQPPLFPHMIWEYTKATGN--YEKqWIDSMDMEMKFW-ENNRTIAIGTHKLFLYK----TLTN-- 293
Cdd:PRK13272 196 YGHIPNGNRTYYLSRSQPPFFSYMVELQAGVEGDaaYQR-YLPQLQKEYAYWmQGSDDLQPGQAARHVVRladgSLLNry 274

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  294 -----CPRPENFLGDFNIGKAAKT--PSDVWRSISSACESGWDFSSRWMHNNDTdLSSIHTDLIIPVDLNVFIANNYRYM 366
Cdd:PRK13272 275 wderdTPRPEAWLHDTRTAAEAKDrpAAEVYRDLRAGAESGWDYSSRWLADGKT-LASIRTTAIVPVDLNSLLYHLERTL 353

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  367 AYYANHFGRFDKSASYRQKYEKLRYAIQEVLWdNNLGAWFDYDisIQKRNL--NFYPSNVYPLML-----EGMDKFADRV 439
Cdd:PRK13272 354 AQACASSGLAACSQDYAALAQQRKQAIDAHLW-NPAGYYADYD--WQTRTLseQVTAAALYPLFAglasdDRAKRTADSV 430

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  440 EDYMKKSGALefvggipSSLPAQSTQQWDFPNVWAPNQHFVIQSFMACNNSFLQQEAKKQAMEFIETVYngmynpiaGLD 519
Cdd:PRK13272 431 RAQLLRPGGL-------ATTALKTGQQWDEPNGWAPLQWVAVDGLRRYGEDALARTIGERFLAQVQALF--------ARE 495

                        410       420       430
                 ....*....|....*....|....*....|....*....
gi 71987755  520 GGVWEKYDArSTNGAPGAGGEYVVQEGFGWTNGAVMDLI 558
Cdd:PRK13272 496 HKLVEKYGL-DGNAAGGGGGEYALQDGFGWTNGVTLMLL 533
treA PRK13271
alpha,alpha-trehalase TreA;
171-558 1.00e-55

alpha,alpha-trehalase TreA;


Pssm-ID: 237326  Cd Length: 569  Bit Score: 198.61  E-value: 1.00e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  171 LIPVQNPFIVPGGRFDVYFYWDTFWIIKGLLVSRMFETTKGIINNFSNLVVTLGYIPNSGNLQLSRRSQPPLFPHMIWEY 250
Cdd:PRK13271 143 LLPLPEPYVVPGGRFREVYYWDSYFTMLGLAESGHWDKVADMVANFAHEIDTWGHIPNGNRSYYLSRSQPPFFALMVELL 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  251 TKATGNYE-KQWIDSMDMEMKFW-ENNRTIAIGTHKLFLYK----TLTN-------CPRPENFLGDFNIGKA--AKTPSD 315
Cdd:PRK13271 223 AQHEGDAAlKQYLPQMQKEYAYWmEGVENLQPGQQEKRVVKlqdgTLLNrywddrdTPRPESWVEDIATAKSnpNRPATE 302

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  316 VWRSISSACESGWDFSSRWMhNNDTDLSSIHTDLIIPVDLNVFIANNYRYMAYYANHFG------RFDKSASYRQKyekl 389
Cdd:PRK13271 303 IYRDLRSAAASGWDFSSRWM-DNPQQLNTIRTTSIVPVDLNALMFKMEKILARASKAAGdnamanQYETLANARQK---- 377

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  390 ryAIQEVLWDNNLGAWFDYDISIQKRNLNFYPSNVYPLML-----EGMDKFADRVEDYMKKSGALefvggipSSLPAQST 464
Cdd:PRK13271 378 --AIEKYLWNDKEGWYADYDLKSHKVRNQLTAAALFPLYVnaaakDRANKVAAATKTHLLQPGGL-------NTTSVKSG 448

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755  465 QQWDFPNVWAPNQHFVIQSFMacnnSFLQQEAkkqAME----FIETVYNgMYNPiaglDGGVWEKYDARSTnGAPGAGGE 540
Cdd:PRK13271 449 QQWDAPNGWAPLQWVATEGLQ----NYGQKEV---AMDvtwrFLTNVQH-TYDR----EKKLVEKYDVSST-GTGGGGGE 515

                        410       420
                 ....*....|....*....|.
gi 71987755  541 YVVQEGFGWTNGA---VMDLI 558
Cdd:PRK13271 516 YPLQDGFGWTNGVtlkMLDLI 536
GDB1 COG3408
Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];
168-408 1.27e-13

Glycogen debranching enzyme (alpha-1,6-glucosidase) [Carbohydrate transport and metabolism];


Pssm-ID: 442634 [Multi-domain]  Cd Length: 353  Bit Score: 72.60  E-value: 1.27e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 168 LYPLIPVQNPFIVPG-GRFDVYFYWDTFWIIKGLLVSRmFETTKGIINNFSNLVVTLGYIPNSGNLQLSRRS----QPPL 242
Cdd:COG3408  11 LRTNTPGDGPTVIAGyPWFSTDWGRDTLIALPGLLLLD-PELARGILRTLARYQEEPGKIPHEVRDGEEPYYgtvdATPW 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 243 FPHMIWEYTKATGNYE--KQWIDSMDMEMKFWENnrtiaiGTHKlflyktltncprpenflGDfnigkaaktpsdvwrSI 320
Cdd:COG3408  90 FIIALGEYYRWTGDLAflRELLPALEAALDWILR------GDRD-----------------GD---------------GL 131

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71987755 321 SSACESGWDfSSRWMhnnDTDLSSIHTDLIIPVDLNVFIANNYRYMAYYANHFGRFDKSASYRQKYEKLRYAIQEVLWDN 400
Cdd:COG3408 132 LEYGRSGLD-NQTWM---DSKVDSVTPRSGALVEVQALWYNALRALAELARALGDPELAARWRELAERLKESFNERFWNE 207


                ....*...
gi 71987755 401 NLGAWFDY 408
Cdd:COG3408 208 ELGYLADA 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH