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rgs-5 RGS domain-containing protein;Regulator of G-protein signaling rgs-5 [ Caenorhabditis elegans ]

Gene ID: 175794, updated on 9-Dec-2024

Summary

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Official Symbol
rgs-5
Official Full Name
RGS domain-containing protein;Regulator of G-protein signaling rgs-5
Primary source
WormBase:WBGene00004348
Locus tag
CELE_B0336.4
See related
AllianceGenome:WB:WBGene00004348
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in protein localization. Predicted to be active in mitochondrion and plasma membrane. Is expressed in nervous system. Orthologous to human AKAP10 (A-kinase anchoring protein 10). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rgs-5 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (5698555..5702305)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transcription initiation factor IIA small chain homolog Neighboring gene THAP-type domain-containing protein Neighboring gene Ubiquitin-like protein atg-12 Neighboring gene Protein SWAP;SURP motif domain-containing protein;Suppressor of white apricot N-terminal domain-containing protein Neighboring gene Large ribosomal subunit protein uL14 Neighboring gene Major sperm protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed. Dong MQ, et al. Genes Dev, 2000 Aug 15. PMID 10950865, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RGS domain-containing protein;Regulator of G-protein signaling rgs-5
NP_001122672.1
  • Confirmed by transcript evidence
NP_498229.3
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    5698555..5702305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001129200.4 → NP_001122672.1  RGS domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001122672.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A9Z1K0
    Conserved Domains (2) summary
    pfam00615
    Location:181 → 303
    RGS; Regulator of G protein signaling domain
    cl02565
    Location:81 → 170
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. NM_065828.9 → NP_498229.3  Regulator of G-protein signaling rgs-5 [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_498229.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q10955
    Conserved Domains (2) summary
    smart00315
    Location:214 → 336
    RGS; Regulator of G protein signalling domain
    pfam00615
    Location:81 → 203
    RGS; Regulator of G protein signaling domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q10955.4

Gene LinkOut

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