GEO DataSet Links for SRA (Select 1165203) - GEO DataSets

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Items: 2

Select item 3015679221.

Heart_20wkC

Organism:: Homo sapiens

Source name:: Heart

Platform:: GPL11154
Series:: GSE64283

Download data: TXT

Sample

Accession:: GSM1567922

ID:: 301567922

SRA Run Selector

Select item 2000642832.

Tissue-specific circular RNA induction during human fetal development

(Submitter supplied) The pervasive expression of circular RNA from protein coding loci is a recently discovered feature of many eukaryotic gene expression programs. Computational methods to discover and quantify circular RNA are essential to the study of the mechanisms of circular RNA biogenesis and potential functional roles they may play. In this paper, we present a new statistical algorithm that increases the sensitivity and specificity of circular RNA detection.by discovering and quantifying circular and linear RNA splicing events at both annotated exon boundaries and in un-annotated regions of the genome Unlike previous approaches which rely on heuristics like read count and homology between exons predicted to be circularized to determine confidence in prediction of circular RNA expression, our algorithm is a statistical approach. more...