GEO DataSets

Comparison of monocytes and macrophages. Samples obtained from 86 patients with acute coronary syndrome. Results used as a reference to compare the performance of Affymetrix (GDS3554) and Illumina (GDS3555) arrays.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 2 cell type, 48 individual, 2 protocol sets

Platform:

GPL1946

Series:

GSE10220

96 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL6097 GPL570

20 Samples

Download data: CEL, TXT

(Submitter supplied) The present study was conducted to compare the ability of Affymetrix and Illumina microarray technologies to characterize the differential gene expression profiles of human monocytes and monocyte-derived-macrophages. Keywords: Type Cross-platform comparison Summary

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3554

Platform:

GPL570

10 Samples

Download data: CEL

(Submitter supplied) In this study we analyzed the gene expression profiles of human monocytes and monocyte-dervied-macrophages. Keywords: Gene expression profiling

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3553

Platform:

GPL1946

96 Samples

Download data: GPR

(Submitter supplied) The present study was conducted to compare the ability of Affymetrix and Illumina microarray technologies to characterize the differential gene expression profiles of human monocytes and monocyte-derived-macrophages. Keywords: Cross-platform comparison

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3555

Platform:

GPL6097

10 Samples

Download data: TXT

Comparison of monocytes and macrophages. Samples obtained from patients with acute coronary syndrome. Results compared to the performance of Affymetrix arrays (GDS3554). The result from two-color arrays (GDS3553) was used as a reference for the Illumina and Affymetrix arrays.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell type, 5 individual sets

Platform:

GPL6097

Series:

GSE10213

10 Samples

Download data: TXT

Comparison of monocytes and macrophages. Samples obtained from patients with acute coronary syndrome. Results compared to the performance of Illumina arrays (GDS3555). The result from two-color arrays (GDS3553) was used as a reference for the Illumina and Affymetrix arrays.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 cell type, 5 individual sets

Platform:

GPL570

Series:

GSE11430

10 Samples

Download data: CEL

(Submitter supplied) The Affymetrix GeneChip® system is a commonly used platform for microarray analysis but the technology is inherently expensive. Unfortunately, changes in experimental planning and execution, such as the unavailability of previously anticipated samples or a shift in research focus, may render significant numbers of pre-purchased GeneChip® microarrays unprocessed before their manufacturer’s expiration dates. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL570 GPL96

12 Samples

Download data: CEL

(Submitter supplied) Microarray technology has had a profound impact on gene expression research. Some studies have questioned whether similar expression results are obtained when the same RNA samples are analyzed on different platforms. The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified as differentially expressed. more...

Organism:

Rattus norvegicus; Homo sapiens

Type:

Expression profiling by array; Expression profiling by RT-PCR

19 related Platforms

943 Samples

Download data: CEL, CSV, GPR, LSR, PDF, TXT, ZIP

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:

GPL570 GPL11154

18 Samples

Download data: CEL, TXT

(Submitter supplied) The RNA samples from HT-29 (ATCC) colon cancer cell line were reverse transcribed to build cDNA libraries and categorized into 3 groups with different concentrations of 5-aza-deoxy-cytidine (5-Aza); in each group three replicative 150 mm cultures were treated with: 1) dimethyl sulfoxide (vehicle alone, 0 μM 5-Aza); 2) 5μM 5-Aza and 3) 10 μM 5-Aza; for five days. This experiment was also performed parallel on a commercial Affymetrix microarray [GSE41364] and the aim of the study was to compare the two platforms on gene expression measurements and differentially expressed gene (DEG) detection. more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL11154

9 Samples

Download data: TXT

(Submitter supplied) The RNA samples from HT-29 (ATCC) colon cancer cell line were reverse transcribed into cDNAs and categorized in 3 groups with different concentrations of 5-aza-deoxy-cytidine (5-Aza); in each group three replicative 150 mm cultures were treated with: 1) dimethyl sulfoxide (vehicle alone, 0 μM 5-Aza); 2) 5μM 5-Aza and 3) 10 μM 5-Aza; for five days We then used Affymetrix microarray platform to profile the gene expression of the 3 HT29 cell groups (3 replicates in each group) in order to search for differentially expressed genes

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL570

9 Samples

Download data: CEL

(Submitter supplied) Microarray expression profiling has become a valuable tool in the evaluation of the genetic consequences of metabolic disease. Although 3’-biased gene expression microarray platforms were the first generation to have widespread availability, newer platforms are gradually emerging that have more up-to-date content and/or higher cost efficiency. Deciphering the relative strengths and weaknesses of these various platforms for metabolic pathway level analyses can be daunting. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Datasets:

GDS3616 GDS3618 GDS3619

4 related Platforms

18 Samples

Download data: CEL, TXT

Analysis of livers from B6.Alb/cre,Pdss2(loxP/loxP) animals following treatment with probucol, an antioxidant/antihyperlipidemic agent. Results used to evaluate the performance of Illumina Mouse WG-6 in comparison to Affymetrix 430 2.0, and Affymetrix Gene 1.0 ST.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 agent, 2 gender, 4 individual sets

Platform:

GPL9526

Series:

GSE18677

6 Samples

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Analysis of livers from B6.Alb/cre,Pdss2(loxP/loxP) animals following treatment with probucol, an antioxidant/antihyperlipidemic agent. Results used to evaluate the performance of Affymetrix Gene 1.0 ST in comparison to Affymetrix 430 2.0, and Illumina Mouse WG-6.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 agent, 2 gender sets

Platform:

GPL9525

Series:

GSE18677

4 Samples

Download data: CEL

Analysis of livers from B6.Alb/cre,Pdss2(loxP/loxP) animals following treatment with probucol, an antioxidant/antihyperlipidemic agent. Results used to evaluate the performance of Affymetrix 430 2.0 in comparison to Affymetrix Gene 1.0 ST, and Illumina Mouse WG-6.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 agent, 2 gender sets

Platform:

GPL9523

Series:

GSE18677

4 Samples

Download data: CEL

(Submitter supplied) Microarrays have been widely used for the analysis of gene expression and several commercial platforms are available. The combined use of multiple platforms can overcome the inherent biases of each approach, and may represent an alternative that is complementary to RT-PCR for identification of the more robust changes in gene expression profiles. In this paper, we combined statistical and functional analysis for the cross platform validation of two oligonucleotide-based technologies, Affymetrix (AFFX) and Applied Biosystems (ABI), and for the identification of differentially expressed genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL570 GPL1426

12 Samples

Download data: CEL

(Submitter supplied) This series represents a set of experiments preformed using RNA isolated from human mammary epithelial cells, human MDA-MB-436 cells and HCC1954 cells. Keywords: parallel sample

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS817 GDS820 GDS823 GDS825

4 related Platforms

22 Samples

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Expression profiling of breast cancer cell lines HCC 1954 and MDA-MB-436 in reference to mammary epithelial cells. Results used to validate a method of comparing data generated from cDNA arrays to that from Affymetrix arrays. The method uses DNA sequence to match probes between platforms.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 2 cell line sets

Platform:

GPL875

Series:

GSE1299

4 Samples

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Expression profiling of breast cancer cell lines HCC 1954 and MDA-MB-436 in reference to mammary epithelial cells. Results used to validate a method of comparing data generated from Affymetrix arrays to that from cDNA arrays. The method uses DNA sequence to match probes between platforms.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 cell line, 2 disease state sets

Platform:

GPL97

Series:

GSE1299

6 Samples

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