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Links from GEO DataSets

Items: 15

1.

Human prostate luminal epithelia adopt a club-like state in response to low androgen levels

(Submitter supplied) Spatial transcriptomics of treatment naive and 5-alpha reductase inhibitior treated human BPH tissue
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
8 Samples
Download data: H5, PNG
2.

Expression data from Incidental vs. Surgical BPH samples

(Submitter supplied) used to identify differences between tissues from patients undergoing surgery for BPH with unresolved symptoms compared to incidental BPH from patients with prostate cancer
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17692
20 Samples
Download data: XLS
Series
Accession:
GSE65343
ID:
200065343
3.

Single Cell Analysis of a Mouse Model of Benign Prostate Hyperplasia Links Oxidative Stress to Progenitor Cell Properties

(Submitter supplied) scRNAseq of prostate cells from 6 and 8 month old Pb-PRL whole prostate mice with enlarged prostate after 28 days of treatment with antioxidant molecule; Anethole tritione (ATT) or coconut oil (vehicle).
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
4 Samples
Download data: H5
Series
Accession:
GSE235859
ID:
200235859
4.

Single-cell RNA-sequencing of adult mouse lower urinary tracts

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
6 Samples
Download data: H5
Series
Accession:
GSE145929
ID:
200145929
5.

Single-cell RNA-sequencing of adult human prostates and urethra (normal and diseased)

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
9 Samples
Download data: H5
Series
Accession:
GSE145928
ID:
200145928
6.

Single-cell RNA-sequencing of adult mouse urethra

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse urethra on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
2 Samples
Download data: H5
Series
Accession:
GSE145865
ID:
200145865
7.

Single-cell RNA-sequencing of adult mouse prostates

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous mouse prostates on the 10x Genomics platform.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
4 Samples
Download data: H5
Series
Accession:
GSE145861
ID:
200145861
8.

Single-cell RNA-sequencing of adult human prostates from organ donors

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates FACS sorted for viability from organ donors (with no known prostatic diseases) on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
6 Samples
Download data: H5
Series
Accession:
GSE145843
ID:
200145843
9.

Single-cell RNA-sequencing of adult human prostates from BPH patients

(Submitter supplied) Single-cell RNA-sequencing was conducted on heterogeneous human prostates FACS sorted for viability from BPH patients on the 10x Genomics platform.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
3 Samples
Download data: H5
Series
Accession:
GSE145838
ID:
200145838
10.

Spatial transcriptomic profiles of prostate tissue obtained from a patient diagnosed with benign prostatic hyperplasia (BPH).

(Submitter supplied) ST profiles reveals the alterations in epithelial cells in Benign Prostatic Hyperplasia.
Organism:
Homo sapiens
Type:
Other
Platform:
GPL20795
1 Sample
Download data: CSV, JPG, JSON, PNG
Series
Accession:
GSE242249
ID:
200242249
11.

Pro-fibrotic and pro-inflammatory genes driven by steroid hormone imbalance in the prostate

(Submitter supplied) The study involved analysis of the effect of testosterone and estradiol hormone pellet implantation with the mouse fibrosis Nanostring panel
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL32922
6 Samples
Download data: RCC, XLSX
Series
Accession:
GSE220444
ID:
200220444
12.

Transcriptional alterations in BPH

(Submitter supplied) We identified a BPH transcriptional signature that included 392 significantly differential expressed genes between BPH and control samples, and validated this BPH transcriptional signature using two independent study cohorts. By performing integrative analysis using transcriptional and methylation profiling, we identified two distinct BPH subtypes, supporting robust biologically distinct subgroups across different data types. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
22 Samples
Download data: TXT, XLSX
13.

Copy number analysis of BPH (Benign Prostatic Hyperplasia)

(Submitter supplied) BPH samples harbored minimal copy number alterations, and the fraction of altered genome was far lower than primary prostate cancer and other neoplastic diseases.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array
Platform:
GPL6801
36 Samples
Download data: CEL, TXT
Series
Accession:
GSE124187
ID:
200124187
14.

Enhanced Reduced Representation Bisulfite Sequencing of BPH and control samples

(Submitter supplied) We investigated the epigenetic landscape of benign prostatic hyperplasia (BPH) by defining the DNA methylation profile of 18 BPH samples and 5 controls from normal transitional zone. We identified 92,046 hypermethylated CpG and 10,117 hypomethylated CpG across different genomic regions in BPH, and hypermethylation was the dominant signal across all genomic regions, even when controlling for bias of CpG-rich loci. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL16791
23 Samples
Download data: TXT
Series
Accession:
GSE123111
ID:
200123111
15.

Single-cell RNAseq of mouse ventral prostate cells in steroid hormone imbalance

(Submitter supplied) We used scRNA-seq to study prostate cellular heterogeneity in mice impanted with testosterone and estradiol pellets.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL30172
4 Samples
Download data: TSV
Series
Accession:
GSE263790
ID:
200263790
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