GEO DataSets

(Submitter supplied) To further understanding of lncRNA and mRNA expression during radioprotectation, we used microarray analysis to determine the differential expression of lncRNAs, and mRNAs in the bone marrow of mice exposed to high-dose IR with and without pretreatment with three types of radioprotectants: Amifostine, CBLB502, and Nilestriol, as well in the hypothalamus of mice exposed to IR with and without pretreatment with amifostine. more...

Organism:

Mus musculus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL20939

14 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL20939 GPL17912

28 Samples

Download data: TXT

(Submitter supplied) To further understanding of miRNA expression during radioprotectation, we used microarray analysis to determine the differential expression of miRNAs in the bone marrow of mice exposed to high-dose IR with and without pretreatment with three types of radioprotectants: Amifostine (WR2721), CBLB502, and Nilestriol, as well in the hypothalamus of mice exposed to IR with and without pretreatment with amifostine. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL17912

14 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:

GPL21103

16 Samples

Download data: TXT

(Submitter supplied) Increasingly, studies have shown that mature spermatozoa contain many transcripts including mRNAs and miRNAs. However, the expression profile of long noncoding RNAs (lncRNAs) in mammalian sperm has not been systematically investigated. Here, we used highly purified RNA to investigate lncRNA expression profiles in mouse mature sperm by stranded-specific RNA-seq. We identified 20907 known and 4088 novel lncRNAs transcripts, and the existence of intact lncRNAs was confirmed by RT-PCR and fluorescence in situ hybridization on two representative lncRNAs. more...

Organism:

Mus musculus

Type:

Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:

GPL21103

6 Samples

Download data: TXT

(Submitter supplied) To explore the critical roles of miRNAs playing in the pathogenesis of hepatocellular carcinoma, the Agilent microarray was used to the profiling of miRNA expression in 7 pairs of HCC and matched adjacent tumor-free tissues.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL20712

14 Samples

Download data: TXT

(Submitter supplied) To explore critical roles of lncRNA and mRNA playing in the pathogenesis of hepatocellular carcinoma, the Agilent microarray was used to simultaneously profile lncRNA and mRNA expression in 7 pairs of HCC and matched adjacent tumor-free tissues.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL21047

14 Samples

Download data: TXT

(Submitter supplied) Total RNA was isolated from leiomyoma and paired myometrium (N=8) and samples from three pairs were subjected to RNA sequencing. After analysis, 5941 lncRNAs (2813 up- and 3128 down-regulated at ≥1.5 fold), 148 miRNAs (56 up- and 96 down-regulated at ≥1.5 fold) and 3855 mRNAs (2030 up- and 1855 down-regulated at ≥1.5 fold) were differentially expressed in leiomyomas. Using QRT-PCR we further confirmed the expression of HULC, lnc-MEG3, LINC00890, TSIX, LINC00473, lnc-KLF9-1 and lnc-POTEM-3 (lncRNA-ATB) in leiomyoma and matched myometrium (N=8). more...

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:

GPL21290

6 Samples

Download data: TXT

(Submitter supplied) Total RNA were extracted from osteoclasts differentiated from RAW264.7 cells at different stages: Monocytes (0h), Pre-osteoclasts (24h), Mature osteoclasts (72h) and activated osteoclasts (96h). LncRNA and mRNA expression profiles were decided by microarray.

Organism:

Mus musculus

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL19286

4 Samples

Download data: TXT

(Submitter supplied) To investigate the aberrant expressed lncRNA and mRNA and identify the potential lncRNA correlated with core mRNA in LSCC, we screened lnRNA and mRNA expression profile in 9 pairs of primary Stage IV LSCC tissues and adjacent non-neoplastic tissues by lncRNA and mRNA integrated microarrays, conducted in-depth integrated bioinformatics analysis of lncRNA and mRNA, and performed qRT-PCR assays to further validate their expressions in an independent cohort of 30 pairs tissue samples

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platform:

GPL17843

18 Samples

Download data: TXT

(Submitter supplied) Purpose: The purpose of this study was to identify aberrantly expressed lncRNAs, circular RNAs and the associated TF‐mRNA network in TSCC. Methods: Tongue tumor noncoding and mRNA profiles of tongue squamous cell carcinoma and adjacent noncancerous tissues were generated by deep sequencing, using Illumina HiSeq 4000. Results: Using an optimized data analysis workflow. Conclusions: we found a profile of dysregulated lncRNAs, TFs and mRNAs that could serve as prospective clinical biomarkers because of their tissue specificity and association with the tumorigenesis and progression of TSCC.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL20301

12 Samples

Download data: XLSX

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platforms:

GPL21265 GPL21994

12 Samples

Download data: TXT

(Submitter supplied) To investigate the lncRNA and mRNA expression profiles in the splenic M-MDSCs of normal and Eg-psc-infected mice, and performed bioinformatics analysis of the differentially expressed lncRNAs to explore the possible biological processes and pathways associated with M-MDSCs.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platform:

GPL21994

6 Samples

Download data: TXT

(Submitter supplied) To investigate the miRNA expression profiles in the splenic M-MDSCs of normal and Eg-psc-infected mice, and performed bioinformatics analysis of the differentially expressed miRNAs to explore the possible biological processes and pathways associated with M-MDSCs.

Organism:

Mus musculus

Type:

Non-coding RNA profiling by array

Platform:

GPL21265

6 Samples

Download data: TXT