U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL21185 GPL570 GPL13534
94 Samples
Download data: CEL, IDAT, TXT
Series
Accession:
GSE110780
ID:
200110780
2.

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease [CBD exp]

(Submitter supplied) The goal of this study was to investigate and correlate differential methylation and expression in cells from the target organ in non-infectious granulomatous lung diseases, specifically sarcoidosis and chronic beryllium disease (CBD). To that end, cells were collected from patients via bronchoalveolar lavage (BAL), and extracted nucleic acids were hybridized to genome-wide arrays. We conclude that there are many genes that are both differentially methylated and expressed in the BAL fluid of patients with granulomatous lung disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
22 Samples
Download data: CEL
Series
Accession:
GSE110779
ID:
200110779
3.

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease [CBD Methylation]

(Submitter supplied) The goal of this study was to investigate and correlate differential methylation and expression in cells from the target organ in non-infectious granulomatous lung diseases, specifically sarcoidosis and chronic beryllium disease (CBD). To that end, cells were collected from patients via bronchoalveolar lavage (BAL), and extracted nucleic acids were hybridized to genome-wide arrays. We conclude that there are many genes that are both differentially methylated and expressed in the BAL fluid of patients with granulomatous lung disease. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
24 Samples
Download data: IDAT
Series
Accession:
GSE110778
ID:
200110778
4.

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease [sarcexp]

(Submitter supplied) The goal of this study was to investigate and correlate differential methylation and expression in cells from the target organ in non-infectious granulomatous lung diseases, specifically sarcoidosis and chronic beryllium disease (CBD). To that end, cells were collected from patients via bronchoalveolar lavage (BAL), and extracted nucleic acids were hybridized to genome-wide arrays. We conclude that there are many genes that are both differentially methylated and expressed in the BAL fluid of patients with granulomatous lung disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL21185
24 Samples
Download data: TXT
Series
Accession:
GSE110777
ID:
200110777
5.

DNA Methylation Changes in Lung Immune Cells are Associated with Granulomatous Lung Disease [sarcmeth]

(Submitter supplied) The goal of this study was to investigate and correlate differential methylation and expression in cells from the target organ in non-infectious granulomatous lung diseases, specifically sarcoidosis and chronic beryllium disease (CBD). To that end, cells were collected from patients via bronchoalveolar lavage (BAL), and extracted nucleic acids were hybridized to genome-wide arrays. We conclude that there are many genes that are both differentially methylated and expressed in the BAL fluid of patients with granulomatous lung disease. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
24 Samples
Download data: IDAT
Series
Accession:
GSE110776
ID:
200110776
6.

Multi-omic signatures of Chronic Beryllium Disease bronchoalveolar lavage cells relate to T cell function and innate immunity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL21185 GPL21145
144 Samples
Download data: IDAT, TXT
Series
Accession:
GSE206719
ID:
200206719
7.

Multi-omic signatures of Chronic Beryllium Disease bronchoalveolar lavage cells relate to T cell function and innate immunity [Expression]

(Submitter supplied) We performed gene expression profiling between Chronic Beryllium Disease, beryllium-sensitized, and healthy control bronchoalveolar cells, and integration with methylation and proteomic data
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL21185
72 Samples
Download data: TXT
Series
Accession:
GSE206715
ID:
200206715
8.

Multi-omic signatures of Chronic Beryllium Disease bronchoalveolar lavage cells relate to T cell function and innate immunity [Methylation]

(Submitter supplied) We performed DNA methylation profiling between Chronic Beryllium Disease, beryllium-sensitized, and healthy control bronchoalveolar cells, and integration with gene expression and proteomic data
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
72 Samples
Download data: IDAT
Series
Accession:
GSE206709
ID:
200206709
9.

Multi-omic signatures of sarcoidosis and progression in bronchoalveolar lavage cells [miRNA]

(Submitter supplied) We profiled DNA methylation, mRNA expression, and miRNA expression from bronchoalveolar lavage cells obtained from 64 sarcoidosis subjects and 16 healthy controls.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by high throughput sequencing
Platform:
GPL24676
72 Samples
Download data: TXT
Series
Accession:
GSE263451
ID:
200263451
10.

Multi-omic signatures of sarcoidosis and progression in bronchoalveolar lavage cells

(Submitter supplied) We profiled DNA methylation, mRNA expression, and miRNA expression from bronchoalveolar lavage cells obtained from 64 sarcoidosis subjects and 16 healthy controls.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24676
46 Samples
Download data: TXT
Series
Accession:
GSE263448
ID:
200263448
11.

Multi-omic signatures of sarcoidosis and progression in bronchoalveolar lavage cells [DNAm]

(Submitter supplied) We profiled DNA methylation, mRNA expression, and miRNA expression from bronchoalveolar lavage cells obtained from 64 sarcoidosis subjects and 16 healthy controls.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
77 Samples
Download data: IDAT
Series
Accession:
GSE263432
ID:
200263432
12.

Gene expression analysis of lung biopsies from patients with two different forms of pulmonary sarcoidosis

(Submitter supplied) Approximately 60-70% of patients with pulmonary sarcoidosis have a good outcome, with disease that resolves spontaneously. It is unclear why some patients progress to fibrotic disease, and there is currently no marker that differentiates these patients from those with self-limiting lung disease. Using the Affymetrix Human Gene 1.0 ST Array, we examined gene expression in lung tissue samples obtained using bronchoscopic transbronchial biopsy from 8 patients with active but self-limiting pulmonary sarcoidosis and 7 with active, progressive, fibrotic pulmonary disease. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3705
Platform:
GPL6244
15 Samples
Download data: CEL
Series
Accession:
GSE19976
ID:
200019976
13.
Full record GDS3705

Progressive pulmonary sarcoidosis

Comparison of lungs from patients with nodular self-limiting pulmonary sarcoidosis (PS) to those with progressive fibrotic PS. About 60-70% of patients with PS have disease that resolves spontaneously, the rest follow a chronic course. Results provide insight into the pathogenesis of progressive PS.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL6244
Series:
GSE19976
15 Samples
Download data: CEL
DataSet
Accession:
GDS3705
ID:
3705
14.

Genome-wide gene expression profile analysis in pulmonary sarcoidosis

(Submitter supplied) We hypothesized that tissue genome-wide gene expression analysis, coupled with gene network analyses of differentially expressed genes, would provide novel insights into the pathogenesis of pulmonary sarcoidosis. Keywords: Disease state analysis
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3580
Platform:
GPL570
12 Samples
Download data: CEL
Series
Accession:
GSE16538
ID:
200016538
15.
Full record GDS3580

Pulmonary sarcoidosis

Analysis of lungs from patients with pulmonary sarcoidosis (PS). PS is characterized by the granulomatous inflammation of the lung. Results provide insight into the molecular pathogenesis of PS.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state sets
Platform:
GPL570
Series:
GSE16538
12 Samples
Download data: CEL
16.

Classical Hodgkin’s Lymphoma: Molecular evidence for specific alterations of circulating T lymphocytes

(Submitter supplied) Gene expression profiles were performed from CD3+ T cells isolated from peripheral blood samples of untreated patients with cHL versus 2 control groups consisting of healthy donors and patients with sarcoidosis. Keywords = Hodgkin’s Lymphoma Keywords = T cell Keywords = immune regulation Keywords: repeat sample
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1419
Platform:
GPL8300
6 Samples
Download data
Series
Accession:
GSE2657
ID:
200002657
17.
Full record GDS1419

Classical Hodgkin's lymphoma: T cell expression profile

Expression profiling of CD3+ T cells isolated from peripheral blood samples of untreated patients with classical Hodgkin's lymphoma. CD3+ T cells from healthy donors and patients with sarcoidosis also examined.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL8300
Series:
GSE2657
6 Samples
Download data
DataSet
Accession:
GDS1419
ID:
1419
18.

Differential transcriptomics in sarcoidosis lung and lymph node granulomas with comparisons to pathogen-specific granulomas

(Submitter supplied) Rationale: Despite the availability of multi-“omics” strategies, insights into the etiology and pathogenesis of sarcoidosis have been elusive. This is partly due to the lack of reliable preclinical models and a paucity of validated biomarkers. As granulomas are a key feature of sarcoidosis, we speculate that direct genomic interrogation of sarcoid tissues, may lead to identification of dysregulated gene pathways or biomarker signatures. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
31 Samples
Download data: FASTA, TSV, TXT
19.

Sarcoidosis + Follow-up study

(Submitter supplied) Sarcoidosis + Follow-up 6 month after Keywords = sarcoidosis Keywords = follow-up Keywords: other
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL91 GPL8300
32 Samples
Download data: CEL
Series
Accession:
GSE1907
ID:
200001907
20.

Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis

(Submitter supplied) Lung macrophages are major participants in the pulmonary innate immune response. In the cystic fibrosis (CF) lung, the inability of lung macrophages to successfully regulate the exaggerated inflammatory response suggests dysfunctional innate immune cell function. In this study, we aim to gain insight into innate immune cell dysfunction in CF by investigating alterations in DNA methylation in bronchoalveolar lavage (BAL) cells, composed primarily of lung macrophages of CF subjects compared with healthy controls. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL21145
16 Samples
Download data: IDAT
Series
Accession:
GSE126646
ID:
200126646
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=1|qty=2|blobid=MCID_675b6f141fc51b7b013a7a3e|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center