GEO DataSets

(Submitter supplied) We carried out a survey of the variation in gene expression patterns in the blood of healthy individuals, by using cDNA microarrays. Our results revealed a surprising consistency in these patterns, but also evidence of distinct patterns of interindividual and temporal variation. Some features of variation in the expression patterns were associated with differences in the cellular composition of the blood sample, with gender, age, and time of day. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3120 GPL3121 GPL3122

147 Samples

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(Submitter supplied) DNA microarray technology is used to determine gene expression profiles of various cell types, especially abnormal cells, such as cancer. By contrast, relatively little attention has been given to expression profiling of normal tissues. Here we describe studies of gene expression in peripheral blood leukocytes (PBL) from normal individuals sampled multiple times over periods ranging from several weeks up to 6 months. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL564

69 Samples

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(Submitter supplied) Oligonucleotide array on glass. Contains 60-mer probes (60-mer). Submitted for Genomics publication Radich et al. The array was custom designed and manufactured by Agilent Technologies. Keywords = human blood expression data

Organism:

Homo sapiens

1 DataSet

2 Series

236 Samples

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(Submitter supplied) Array hybridizations profiling diverse human tissues; for each array the human tissue RNA is hybridized against a universal reference RNA. Experiments 1-3 are replicates of universal reference RNA vs. genomic DNA hybridizations, used to estimate transcript abundance. Arrays 4-8 are tissue RNA vs. genomic DNA hybridizations, carried out to evaluate the method for estimating transcript abundance (see manuscript for details). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL1827

8 Samples

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(Submitter supplied) Array hybridizations profiling diverse human tissues; for each array the human tissue RNA is hybridized against a universal reference RNA. Series_type: Logical set Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Datasets:

GDS1085 GDS1088

5 related Platforms

123 Samples

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Expression profiling of 115 samples from 35 different types of normal tissues. Samples obtained by surgery or autopsy, and evaluated by pathologists. Results provide insight into the molecular organization of diverse cell types, and provide a baseline for comparison to diseased tissues.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 4 tissue sets

Platform:

GPL1826

Series:

GSE2193

11 Samples

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Expression profiling of 115 samples from 35 different types of normal tissues. Samples obtained by surgery or autopsy, and evaluated by pathologists. Results provide insight into the molecular organization of diverse cell types, and provide a baseline for comparison to diseased tissues.

Organism:

Homo sapiens

Type:

Expression profiling by array, log ratio, 20 tissue sets

Platform:

GPL1823

Series:

GSE2193

35 Samples

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(Submitter supplied) Natural variation in gene expression among healthy human individuals has been largely unexplored. In order to understand the genetic basis of variation in gene expression between normal human individuals, we need to obtain genome-wide expression data from various populations. Studies in monozygotic twins could enable us to estimate the size of the contribution of genetic and environmental factors to the natural variation in gene expression. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL8300 GPL91

15 Samples

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(Submitter supplied) We used quantitative RNA expression profiling on the Affymetrix U133 human expression array to validate quantitative expression results obtained with the tissue preservative RNALater against snap frozen and fresh tissues as a means of routine tissue collection and temporary storage. By using split samples from a homogenous tissue (uterine myometrium), and including duplicates within each processing group compared, we were able to undertake a formal ANOVA analysis comparing the magnitude of result variation contributed by sample source (different patients), processing protocol (fresh vs. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS1972

Platform:

GPL96

24 Samples

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Analysis of uterine myometrial tissue specimens stored in RNAlater preservative for 24 or 74 hours at room temperature. Results indicate RNALater did not contribute any systematic shift in quantitative RNA expression results relative to alternative tissue processing methods (fresh, snap-frozen).

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 protocol, 3 time sets

Platform:

GPL96

Series:

GSE1296

24 Samples

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(Submitter supplied) Consistent with clinical observations that posterior uveitis frequently involves the retinal vasculature and recent recognition of vascular heterogeneity, we hypothesized that retinal vascular endothelium was a cell population of unique molecular phenotype. Donor-matched cultures of primary retinal and choroidal endothelial cells from 6 human cadavers were incubated with either Toxoplasma gondii tachyzoites (10:1, parasite:cell) or Escherichia coli lipopolysaccharide (100 ng/mL); control cultures were simultaneously incubated with medium. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL201

46 Samples

Download data: CEL

(Submitter supplied) Comparison of gene expression in CD34+ cells from bone marrow and G-CSF-mobilized peripheral blood to investigate why the latter are optimal for allogeneic transplant recipients. Keywords: other

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS53

Platform:

GPL80

5 Samples

Download data: CEL

Comparison of gene expression in CD34+ cells from bone marrow and G-CSF-mobilized peripheral blood to investigate why the latter are optimal for allogeneic transplant recipients.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell type sets

Platform:

GPL80

Series:

GSE500

5 Samples

Download data: CEL

(Submitter supplied) The in-house microarray consists of 167 RT-PCR derived DNA fragments representing 167 ORFs from bovine. The DNA fragments are printed 4 times on the surface of the microarray (four-replicate blocks). The 167 immune and endocrine genes grouped into the following categories: cytokine genes, chemoattractants or chemokines and their respective receptor genes, immune regulatory genes, T-cell associated genes, pattern recognition or innate host defense genes, immunglobin (Ig) or Ig-related genes, complement genes, antigen processing or presenting genes, and genes encoding endocrine hormones or their receptors. more...

Organism:

Arabidopsis thaliana; Bos taurus

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

34 Samples

Download data: CEL

(Submitter supplied) To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge, post-challenge compared to pre-challenge

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

18 Samples

Download data: CEL

(Submitter supplied) Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using non-globin reduced PAXgene (PAX.NGR) tubes Blood was collected immediately prior to, and two hours after challenge

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

8 Samples

Download data: CEL

(Submitter supplied) Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using globin reduced PAXgene (PAX.GR) tubes

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

8 Samples

Download data: CEL

(Submitter supplied) Background: Allergen inhalation challenge in mild asthmatics induces airflow obstruction, airway hyperresponsiveness and inflammation, providing a model for hypothesis-generating experiments to understand regulation of these responses. We have sought to evaluate the peripheral whole blood transcriptome, post-challenge compared to pre-challenge, and to determine the effect of globin mRNA reduction methodology. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6244

30 Samples

Download data: CEL

(Submitter supplied) Smallpox has played an unparalleled role in human history and remains a significant potential threat to public health. Despite the historical significance of this disease, we know little about the underlying pathophysiology or the virulence mechanisms of the causative agent, variola virus. To improve our understanding of variola pathogenesis and variola-host interactions, we examined the molecular and cellular features of hemorrhagic smallpox in cynomolgus macaques. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platforms:

GPL3347 GPL3093 GPL3346

167 Samples

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