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Items: 3

1.

Bioenergetic programs of cancellous and cortical bone are distinct and differ with age and mechanical loading

(Submitter supplied) Mechanical loading induces bone formation in young rodents, but mechanoresponsiveness is reduced with age. Glycolytic activity and mitochondrial dysfunction increase with age and may change bone mechanotransduction. To evaluate load-induced changes to bioenergetic activity in young and adult animals, we loaded the tibia of 10-wk and 26-wk female mice and examined transcriptomic responses at the mid-diaphysis, metaphyseal cortical shell, and cancellous core. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
150 Samples
Download data: XLSX
Series
Accession:
GSE281942
ID:
200281942
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

26wk_Metaphyseal Shell_Contralateral Control Limb _3h _Animal3h06

Organism:
Mus musculus
Source name:
Metaphyseal Shell
Platform:
GPL19057
Series:
GSE281942
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Sample
Accession:
GSM8633361
ID:
308633361
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db=gds|term=GSM8633361[Accession]|query=1|qty=2|blobid=MCID_674f81a168e51b28f58224b2|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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