GSM773327[Accession] - GEO DataSets

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Items: 4

Select item 2000311931.

A Robust Induction of Type III Interferons and Chemokines Defines a Unique Pattern of Hepatic Innate Immunity in Response to Hepatitis C Virus Infection

(Submitter supplied) Recent identification of IL28B gene polymorphisms associated with hepatitis C virus (HCV) clearance suggests a role for type III interferons (IFNs) in hepatitis C infection. The function of type III IFNs in intrinsic antiviral immunity is poorly understood. Here we show that HCV infection of primary human hepatocytes results in a robust induction of type III but not type I IFNs, leading to IFN- stimulated gene (ISG) expression. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4390
Platform:: GPL570
15 Samples

Download data: CEL, CHP

Series

Accession:: GSE31193

ID:: 200031193

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 43902.

Primary hepatocyte response to interferon-α or interleukin 28B: time course

Analysis of primary hepatocytes up to 24 hrs after treatment with cytokines: interferon (IFN)-α or interleukin 28B (IL28B, a type III IFN). Members of type III IFN system possess antiviral activities against Hepatitis C Virus (HCV). Results provide insight into role of III IFNs in HCV infection.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 3 agent, 3 time sets

Platform:: GPL570
Series:: GSE31193
15 Samples

Download data: CEL, CHP

DataSet

Accession:: GDS4390

ID:: 4390

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...