GSM6813269[Accession] - GEO DataSets

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Items: 4

Select item 2002034781.

Recycling of parental histones preserves the epigenetic landscape during embryonic development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL19132 GPL25244 GPL21306
154 Samples

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Accession:: GSE203478

ID:: 200203478

PubMed Full text in PMC Similar studies

Select item 2002034762.

Recycling of parental histones preserves the epigenetic landscape during embryonic development (CUT&Tag)

(Submitter supplied) Epigenetic inheritance during DNA replication requires an orchestrated assembly of nucleosomes from parental and newly synthesized histones. We analyzed Drosophila HisC mutant embryos harboring a deletion of all canonical histone genes, in which nucleosome assembly relies on parental histones from cell cycle 14 onwards. Lack of new histone synthesis and parental histone recycling leads to more accessible chromatin and reduced nucleosome occupancy. more...