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Items: 4

1.

Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19132 GPL13304
122 Samples
Download data: BED, BW, H5, TSV
Series
Accession:
GSE200875
ID:
200200875
2.

Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development [ChIP-seq]

(Submitter supplied) While enhancers are often regulated at the level of accessibility by pioneer factors, promoters tend to be constitutively accessible and poised for activation by paused Pol II — thus are often not considered as sites of developmental regulation. Here we show that the accessibility of promoters and the acquisition of paused Pol II can also be subject to developmental regulation by pioneer factors. We show that Lola-I, a Drosophila zinc finger transcription factor, is ubiquitously expressed at the end of embryogenesis and causes its target promoters to become accessible and acquire paused Pol II throughout the embryo. more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19132 GPL13304
33 Samples
Download data: BED, BW
Series
Accession:
GSE200870
ID:
200200870
3.

Illumina HiSeq 2000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
910 Series
18316 Samples
Download data
Platform
Accession:
GPL13304
ID:
100013304
4.

Dme_emb_14-17h_Rpb3_1

Organism:
Drosophila melanogaster
Source name:
Pol II ChIP in 14-17hrs OregonR embryos Rep1
Platform:
GPL13304
Series:
GSE200870 GSE200875
Download data: BW
Sample
Accession:
GSM6045764
ID:
306045764
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Supplemental Content

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