GSM595007[Accession] - GEO DataSets

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Items: 4

Select item 2000241881.

Atorvastatin, rosuvastatin and rifampicin effect on human primary hepatocyte transcriptome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platforms:: GPL570 GPL8091
111 Samples

Download data: CEL, TXT

Series

Accession:: GSE24188

ID:: 200024188

Select item 2000241862.

Atorvastatin, rosuvastatin and rifampicin effect on human primary hepatocyte transcriptome [Steroltalk platform]

(Submitter supplied) With particular emphasis on interactions between cholesterol homeostasis and drug metabolism we investigate the transcriptome of human primary hepatocytes treated by two commonly prescribed cholesterol lowering drugs atorvastatin and rosuvastatin and by rifampicin that serves as an outgroup as well as a model substance for induction of nuclear receptor PXR. Expression profiling with dedicated Steroltalk cDNA arrays shows that statins induce extensive transcriptome changes.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8091
71 Samples

Download data: TXT

Series

Accession:: GSE24186

ID:: 200024186

Select item 1000080913.

Steroltalk v2 human

(Submitter supplied) Spotter: Biorobotics Microgrid II Number of pins: 2 Probes: cDNA Slides: Corning Gaps II Number of probes (for each array): 304 human in 3 replicas, 528 control Number of blocs: 6 per array, 2 arrays per slide Block size: 16x15 spots (height x width) Pitch between spots: 260 µm Spot size: between 110 and 170 µm Printed: 55 slides (110 chips) Process length: ~ 19H Humidity: 40% in the room Temperature: 20°C+/-0.5 Buffer conditions: formamide 50%, Chaps 1%

Organism:: Homo sapiens

2 Series
71 Samples

Download data: TXT

Platform

Accession:: GPL8091

ID:: 100008091

Select item 3005950074.

Rosuvastatin 48h donor 271 [Steroltalk]

Organism:: Homo sapiens

Source name:: Cells treated with rosuvastatin for 48h (channel 1) Mix of untreated cells from all donors and other human liver RNA samples [reference] (channel 2)