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Items: 3

1.

Interactomics Analyses of Wild-type and Mutant A1CF Reveal Diverged Functions in Regulating Cellular Lipid Metabolism

(Submitter supplied) Population genetic studies highlight a missense variant (G398S) of A1CF that is strongly associated with higher levels of blood triglycerides (TGs) and total cholesterol (TC). Functional analyses suggest that the mutation accelerates the secretion of very low-density lipoprotein (VLDL) from the livers by an unknown mechanism. Here, we used multi-omics approaches to interrogate the functional difference between the WT and mutant A1CF. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21697
12 Samples
Download data: DIFF, XLSX
Series
Accession:
GSE152807
ID:
200152807
2.

NextSeq 550 (Homo sapiens)

Platform
Accession:
GPL21697
ID:
100021697
3.

FS71_WT-D1

Organism:
Homo sapiens
Source name:
Huh7 cell clone containing WT A1CF inducible expression construct induced with doxycycline
Platform:
GPL21697
Series:
GSE152807
Download data
Sample
Accession:
GSM4626773
ID:
304626773
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