GSM4431269[Accession] - GEO DataSets - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 4

Select item 2001474551.

An epigenetic vulnerability in PI3K/AKT inhibition resistant cancers is targetable by both bromodomain and HDAC inhibitors

(Submitter supplied) Acquisition of resistance to PI3K/AKT-targeted monotherapy regardless of cancer types implies the existence of common mechanisms. Here we demonstrate that while causing glycolysis crisis, acetyl-CoA shortage and global decrease of histone acetylation, PI3K/AKT inhibitors induce drug resistance by selectively augmenting CBP/p300, H3K27 acetylation and BRD4 binding at genomic loci of a subset of growth factor and receptor (GF/R) genes. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL20301
32 Samples

Download data: BW

Series

Accession:: GSE147455

ID:: 200147455

SRA Run Selector

Select item 2001372092.

Bromodomain and HDAC inhibitors equivalently suppress PI3K/AKT inhibition resistance in cancers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21290 GPL20301
56 Samples

Download data: BW, XLS

Series

Accession:: GSE137209

ID:: 200137209

Select item 1000203013.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8517 Series
195568 Samples

Platform

Accession:: GPL20301

ID:: 100020301

Select item 3044312694.

PC3 GDC-resist p300 rep2

Organism:: Homo sapiens

Source name:: prostate

Platform:: GPL20301
Series:: GSE137209 GSE147455

Download data: BW

Sample

Accession:: GSM4431269

ID:: 304431269

SRA Run Selector

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Supplemental Content

Filters: Manage Filters

Find related data

Search details

Important Links

Recent activity

Clear Turn Off Turn On

GSM4431269[Accession] (4)
GEO DataSets

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Genes & Expression > Gene Expression Omnibus (GEO) Datasets