GEO DataSets

(Submitter supplied) We investigated whether the miRNA expression could distinguish lung cancers from normal tissues, examining 116 pairs of primary lung cancers with their corresponding adjacent normal lung tissues collected a minimum of 5 cm from the tumor. Our analysis identified a five microRNA classifier could distinguish malignant lung cancer lesions from adjacent normal tissues. SCLC could be distinguished from non small lung cancer by microRNAs profiling. more...

Organism:

Mus musculus; Homo sapiens; Rattus norvegicus

Type:

Non-coding RNA profiling by array

Platform:

GPL8176

375 Samples

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(Submitter supplied) Altogether 924 mature miRNA sequences were assembled and integrated into our miRNA microarray design, these comprised 677 human (including a further 122 predicted miRNA sequences from published references (Xie et al., Nature 2005,434:338-345 ), 292 rat and 461 mouse mature miRNAs from the miRNA Registry (Sanger, accessed Aug. 2007). In addition, we designed 8 short oligonucleotides that possessed no homology to any known RNA sequence and we produced their corresponding synthetic miRNAs by in vitro transcription using Ambion's miRNA Probe Construction kit (Cat. more...

Organism:

Homo sapiens; Mus musculus; Rattus norvegicus

1 Series

375 Samples

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