GSM3533302[Accession] - GEO DataSets

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Items: 4

Select item 2001244391.

Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia

(Submitter supplied) Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons. While several pathogenic mutations have been identified, the vast majority of ALS cases have no family history of disease. Thus, for most ALS cases, the disease may be a product of multiple pathways contributing to varying degrees in each patient. Using machine learning algorithms, we stratified the transcriptomes of 148 ALS postmortem cortex samples into three distinct molecular subtypes. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
176 Samples

Download data: TXT

Series

Accession:: GSE124439

ID:: 200124439

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001378102.

NYGC ALS Consortium data

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below. Consortium contacts: Maria Pedersen: [email protected] Hemali Phatnani: [email protected] NYGC ALS Consortium: [email protected]