GSM3394843[Accession] - GEO DataSets

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Items: 4

Select item 2001201431.

Temporal auto-regulation during PU.1 locus SubTAD formation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16791 GPL18573
37 Samples

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Series

Accession:: GSE120143

ID:: 200120143

PubMed Similar studies

Select item 2001106832.

Temporal auto-regulation during PU.1 locus SubTAD formation (4C-seq)

(Submitter supplied) Epigenetic control of gene expression occurs through discrete spatial chromosomal units called topologically associating domains (TADs), but the exact spatial requirements of most genes are unknown; this is of particular interest for genes involved in disease. We therefore applied high-resolution chromosomal conformation capture-sequencing to map the three-dimensional (3D) organization of the locus encoding the key myeloid transcription factor PU.1 in healthy monocytes and acute myeloid leukemia (AML) cells. more...