GSM3108979[Accession] - GEO DataSets

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Items: 4

Select item 2000976981.

Epigenetic regulation of in vivo B cell Differentiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL17021
25 Samples

Download data: BW

Series

Accession:: GSE97698

ID:: 200097698

PubMed Full text in PMC Similar studies

Select item 2000976962.

Chemical Inhibition of Ezh2 Alters Ex Vivo B cell Differentiation and Gene Expression Dynamics

(Submitter supplied) To understand the role of Ezh2 in B cell differentiation B cells were stimulated ex vivo with LPS, Il2, and Il5 in the presence of DMSO or the selective Ezh2 inhibitor GSK343. Following 3 days culture, activated B cells and Plasmablasts were FACS isolated and RNA-seq was performed to identify the molecular effects of Ezh2 inhibition on B cell subsets during differentiation.