GSM310374[Accession] - GEO DataSets

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Items: 4

Select item 2000123561.

Analysis of Aiolos and OBF-1 deletions in bone marrow from 7 week old mice

(Submitter supplied) The chromatin regulator Aiolos and the transcriptional coactivator OBF-1 have been implicated in regulating aspects of B cell maturation and activation. Mice lacking either of these factors have a largely normal early B cell development. However, when both factors are eliminated simultaneously a block is uncovered at the transition between pre-B and immature B cells, indicating that these proteins exert a critical function in developing B lymphocytes. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3473
Platform:: GPL339
8 Samples

Download data: CEL, EXP

Series

Accession:: GSE12356

ID:: 200012356

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 34732.

Aiolos/OBF-1 double null mutation effect on bone marrow pre-BII cells

Analysis of bone marrow pre-BII cells from Aiolos/OBF-1 double null mutants. Aiolos is a chromatin regulator, OBF-1 a transcriptional activator. Small pre-BII to immature B cell transition is impaired in the double mutants. Results provide insight into the role of Aiolos and OBF-1 in pre-BII cells.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 4 genotype/variation sets

Platform:: GPL339
Series:: GSE12356
8 Samples

Download data: CEL, EXP

DataSet

Accession:: GDS3473

ID:: 3473

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 1000003393.

[MOE430A] Affymetrix Mouse Expression 430A Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html The GeneChip Mouse Genome 430A 2.0 Array is accessioned in GEO as GPL8321. June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Mouse Genome 430A Array is a single array representing approximately 14,000 well-characterized mouse genes that can be used to explore biology and disease processes. more...