GEO DataSets

(Submitter supplied) Desmoids tumors (DTs) are rare mesenchymal infiltrative lesions that exhibit high risk of local recurrence despite surgery with negative margins. Mutations in CTNNB1 gene encoding for β-catenin are typically carried by most sporadic DTs but the evidences in support to the clinical/biological role of these mutations are contrasting. Our work is the first study specifically investigating if mutation type could influence the stability of the β-catenin structure, its affinity for α-catenin, as well as the pattern of gene expression and could in turn guide the behavior of the disease.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL14951

33 Samples

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(Submitter supplied) see manufacturer's website

Organism:

Homo sapiens

154 Series

1 Related Platform

8763 Samples

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