GSM2665442[Accession] - GEO DataSets

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Items: 4

Select item 2000999561.

Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by array

Platforms:: GPL17021 GPL11180
75 Samples

Download data: BEDGRAPH, CEL, VCF

Series

Accession:: GSE99956

ID:: 200099956

Select item 2000999342.

Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours

(Submitter supplied) Mutations and expression changes of epigenetic modifiers are pervasive in human tumours, making epigenetic factors attractive as antitumour targets. However, the mutational landscape of tumours correlates with the chromatin state of their cell-of-origin, raising the concern that targeting epigenetic factors might alter the mutational burden and possibly aggravate disease progression. Nonetheless, a causal link between changes in chromatin in tissues and the mutational landscape of their cognate tumours has not yet been established. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
14 Samples

Download data: CEL

Series

Accession:: GSE99934

ID:: 200099934

Select item 1000111803.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site