GSM2424342[Accession] - GEO DataSets

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Items: 4

Select item 2000922361.

Hypothalamic oxidative stress provokes leptin and insulin resistance

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11202
12 Samples

Download data: TXT

Series

Accession:: GSE92236

ID:: 200092236

Analyze with GEO2R

Select item 2000922352.

Hypothalamic oxidative stress provokes leptin and insulin resistance [hypothlamus]

(Submitter supplied) The relationship between loss of hypothalamic function and onset of diabetes mellitus remains elusive. Therefore, we generated a targeted oxidative-stress murine model utilizing conditional knockout of selenocysteine-tRNA (Trsp) using rat insulin promoter-driven-Cre (RIP-Cre). These Trsp-knockout (TrspRIPKO) mice exhibit deletion of Trsp in both hypothalamic cells and pancreatic β-cells leading to increased hypothalamic oxidative stress and severe insulin resistance. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11202
6 Samples

Download data: TXT

Series

Accession:: GSE92235

ID:: 200092235

Analyze with GEO2R

Select item 1000112023.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/