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Items: 3

1.

Differential Toxicity of Nuclear RNA Foci Versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

(Submitter supplied) Nuclear RNA foci are often associated with mis-regulation of RNA processing in repeat expansion diseases. Here we report transcriptomic analysis of flies carrying expanded G4C2 repeats, the most common genetic cause of FTD/ALS. By obtaining an average of 32 million reads per library, we show that the presence of numerous nuclear G4C2 repeat RNA foci does not cause extensive changes in RNA processing in this model organism.
Organism:
Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19132
16 Samples
Download data: TXT
Series
Accession:
GSE72771
ID:
200072771

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
487 Series
11751 Samples
Download data
Platform
Accession:
GPL19132
ID:
100019132

3.

Chrom2-5R-Rep3

Organism:
Drosophila melanogaster
Source name:
Chrom2-5R_fly heads
Platform:
GPL19132
Series:
GSE72771
Download data: TXT
Sample
Accession:
GSM1870036
ID:
301870036

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db=gds|term=GSM1870036[Accession]|query=1|qty=2|blobid=MCID_6748ef05462e1a751e1505c8|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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