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Items: 4

1.

Emergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
synthetic construct; Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array; Methylation profiling by genome tiling array
Platforms:
GPL13534 GPL6244 GPL14613
81 Samples
Download data: CEL, IDAT
Series
Accession:
GSE66078
ID:
200066078
2.

Emergence of a developmental stage-dependent human liver disease signature demonstrated by directed differentiation of alpha-1 antitrypsin deficient iPS cells [HumanMethylation450]

(Submitter supplied) We monitored 9 pluripotent stem cell lines across three time points of hepatic directed differentiation, representing 3 developmental stages: undifferentiated (T0), definitive endoderm (T5), and early hepatocyte (T24). ESCs (n=3) and patient-derived normal (n=3) or PiZZ (n=3) iPSCs were analyzed in the undifferentiated state (T0), after differentiation to definitive endoderm (T5), and upon reaching hepatic stage (T24) for a total of 27 samples. more...
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13534
27 Samples
Download data: IDAT, TXT
Series
Accession:
GSE66077
ID:
200066077
3.

Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)

(Submitter supplied) 1 difference between HumanMethylation450_15017482_v.1.1.bpm and HumanMethylation450_15017482_v.1.2.bpm: 1.1: 41636384,NEGATIVE,-99,Negative 604 1.2: 41636384,RESTORATION,Green,Restore Protocol: See manufacturer's website
Organism:
Homo sapiens
1686 Series
1 Related Platform
119315 Samples
Download data: BPM, CSV, TXT, XLSX
Platform
Accession:
GPL13534
ID:
100013534
4.

iPSC wild-type T0 1

Organism:
Homo sapiens
Source name:
wild-type skin fibroblasts
Platform:
GPL13534
Series:
GSE66077 GSE66078
Download data: IDAT
Sample
Accession:
GSM1613989
ID:
301613989
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