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Items: 3

1.

Prevalent p53 gain-of-function mutants co-opt epigenetic pathways to drive cancer growth

(Submitter supplied) We investigated the genomewide binding pattern of prevalent p53 gain-of-function (GOF) mutants by ChIP-seq, in a panel of breast cancer cell lines. We assessed the genomewide changes of H3K4me3 upon GOF p53 knockdown in MDA-MB-468 breast cancer cells bearing the p53 R273H mutation.
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL19057
15 Samples
Download data: BEDGRAPH, BW, TXT
Series
Accession:
GSE59176
ID:
200059176
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

WT mouse PolyA+ RNAseq

Organism:
Mus musculus
Source name:
WT mouse
Platform:
GPL19057
Series:
GSE59176
Download data: BEDGRAPH
Sample
Accession:
GSM1572252
ID:
301572252
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db=gds|term=GSM1572252[Accession]|query=1|qty=3|blobid=MCID_674f83ea68e51b28f5825c89|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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