GSM1342895[Accession] - GEO DataSets

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Items: 4

Select item 2000557591.

Promoter methylome and integrative transcriptome profiling identify key epigenetics-regulated genes in human HCCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL11154 GPL9052
32 Samples

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Series

Accession:: GSE55759

ID:: 200055759

PubMed Full text in PMC Similar studies

Select item 2000557582.

Promoter methylome and integrative transcriptome profiling identify key epigenetics-regulated genes in human HCCs [expression]

(Submitter supplied) Hepatocellular carcinoma (HCC) is one of the most common and lethal cancers worldwide and has a poor prognosis. Promoters represent an essential regulatory element of gene transcription in human genome. In order to understand the promoter methylation in relation with gene transcription in HCCs, We applied a liquid hybridization capture-based bisulfite sequencing (LHC-BS) approach to examine the promoter methylome of HCCs, for which we customized 150,407 capture probes and enabled coverage of 91.8% of the RefSeq gene promoters within human genome. more...