GSM1260044[Accession] - GEO DataSets

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Items: 3

Select item 2000521241.

TAp73 is essential for germ cell adhesion and maturation in testis

(Submitter supplied) A core evolutionary function of the p53 family is to protect the genomic integrity of gametes. However, the role of p73 in the male germline is unknown. Here we uncover that TAp73 unexpectedly functions as adhesion and maturation factor of the seminiferous epithelium orchestrating spermiogenesis. TAp73KO and p73KO mice, but not ΔNp73KO mice, display a ‘near-empty seminiferous tubule’ phenotype due to massive premature loss of immature germ cells. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11202
12 Samples

Download data: TXT

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Accession:: GSE52124

ID:: 200052124

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000112022.

Agilent-026655 Whole Mouse Genome Microarray 4x44K v2 (Probe Name version)

(Submitter supplied) *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL10333. Protocol: see manufacturer's web site at http://www.agilent.com/