GEO DataSets

(Submitter supplied) High-fat diet and obesity are high risk factors for colorectal cancer. The underlying mechanism is still unclear. Environmental factors alter the epigenome to affect gene expression thus the phenotype. In response to external stimuli, the cis-regulatory regions, especially enhancer loci, are key elements for regulating selective gene expression. We thus explored the effects of high-fat diet and the accompanying obesity on gene expression and the enhancer landscape in colon epithelium. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5264

Platform:

GPL7202

11 Samples

Download data: TXT

Analysis of colon epithelium from NAG-1 (NSAID-activated gene-1) transgenics and wild-type C57BL/6J animals fed a high-fat diet for 20wk. The NAG-1 transgenics did not gain weight as their wild-type counterparts did. Results provide insight into the molecular impact of obesity on colonic epithelium.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 genotype/variation, 2 protocol sets

Platform:

GPL7202

Series:

GSE46843

11 Samples

Download data: TXT

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...

Organism:

Mus musculus

16 DataSets

654 Series

1 Related Platform

10680 Samples

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