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Items: 13

1.

The chromatin remodeler ATRX binds to atypical chromatin domains at the 3’ exons of ZNF genes to preserve H3K9me3 enrichment

(Submitter supplied) Here, we report that ATRX co-localizes with the H3K9-methyl transferase SETDB1 (also known as ESET), the co-repressor TRIM28 (also known as KAP1), and the transcription factor ZNF274 at 3’ exons of Zinc Finger Genes (ZNFs) containing an atypical H3K9me3/H3K36me3 chromatin signature. Disruption of ATRX and ZNF274 leads to a significant reduction of H3K9me3, particularly at the 3’ ZNF exons and other atypical chromatin regions, higher percentages of DNA damage, and defects in cell cycle. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL16791
10 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE70920
ID:
200070920

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Homo sapiens)

Organism:
Homo sapiens
12602 Series
343758 Samples
Download data
Platform
Accession:
GPL18573
ID:
100018573

3.

Illumina HiSeq 2500 (Homo sapiens)

Organism:
Homo sapiens
12216 Series
349569 Samples
Download data
Platform
Accession:
GPL16791
ID:
100016791

4.

LAN6-ATRX-XL-MNase_ChIP

Organism:
Homo sapiens
Source name:
LAN6
Platform:
GPL18573
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM2066632
ID:
302066632

SRA Run Selector

5.

LAN6-Input_control-XL-MNase_ChIP

Organism:
Homo sapiens
Source name:
LAN6
Platform:
GPL18573
Series:
GSE70920
Download data
Sample
Accession:
GSM2066631
ID:
302066631

SRA Run Selector

6.

LAN6-H3K9me3-Native_ChIP

Organism:
Homo sapiens
Source name:
LAN6
Platform:
GPL16791
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM2066634
ID:
302066634

SRA Run Selector

7.

LAN6-Input_control-Native_ChIP

Organism:
Homo sapiens
Source name:
LAN6
Platform:
GPL16791
Series:
GSE70920
Download data
Sample
Accession:
GSM2066633
ID:
302066633

SRA Run Selector

8.

K562-H3K9me3-ATRX_KO-Native_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM1821908
ID:
301821908

SRA Run Selector

9.

K562-H3K9me3-Cas9_control-Native_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM1821907
ID:
301821907

SRA Run Selector

10.

K562-Input_control-Native_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data
Sample
Accession:
GSM1821906
ID:
301821906

SRA Run Selector

11.

K562-ATRX_Abcam-XL-MNase_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM1821905
ID:
301821905

SRA Run Selector

12.

K562-ATRX_SC-XL-MNase_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data: BED, BIGWIG
Sample
Accession:
GSM1821904
ID:
301821904

SRA Run Selector

13.

K562-Input_control-XL-MNase_ChIP

Organism:
Homo sapiens
Source name:
K562
Platform:
GPL16791
Series:
GSE70920
Download data
Sample
Accession:
GSM1821903
ID:
301821903

SRA Run Selector

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