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Items: 19

1.

Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase over-expressing mice defines an immune-associated gene signature linked to tamoxifen resistance

(Submitter supplied) To investigate response or resistance to endocrine therapy, mice with targeted over-expression of Esr1 or CYP19A1 to mammary epithelial cells were employed, representing two direct pathophysiological interventions in estrogen pathway signaling. Both Esr1 and CYP19A1 over-expressing mice responded to letrozole with reduced HAN prevalence and decreased mammary epithelial cell proliferation. CYP19A1 over-expressing mice were tamoxifen-sensitive but Esr1 over-expressing mice were tamoxifen-resistant. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
17 Samples
Download data: TXT
Series
Accession:
GSE63857
ID:
200063857
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

Paired-end_CERM_rep3

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558529
ID:
301558529
4.

Paired-end_CERM_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558528
ID:
301558528
5.

Paired-end_CERM_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558527
ID:
301558527
6.

Paired-end_BRCA_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558526
ID:
301558526
7.

Paired-end_BRCA_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558525
ID:
301558525
8.

Paired-end_AROM_rep3

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558524
ID:
301558524
9.

Paired-end_AROM_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558523
ID:
301558523
10.

Paired-end_AROM_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558522
ID:
301558522
11.

Paired-end_WT

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558521
ID:
301558521
12.

Single-end_CERM_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558520
ID:
301558520
13.

Single-end_CERM_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558519
ID:
301558519
14.

Single-end_BRCA_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558518
ID:
301558518
15.

Single-end_BRCA_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558517
ID:
301558517
16.

Single-end_AROM_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558516
ID:
301558516
17.

Single-end_AROM_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558515
ID:
301558515
18.

Single-end_WT_rep2

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558514
ID:
301558514
19.

Single-end_WT_rep1

Organism:
Mus musculus
Source name:
mammary glands
Platform:
GPL13112
Series:
GSE63857
Download data
Sample
Accession:
GSM1558513
ID:
301558513
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Supplemental Content

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