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Items: 10

1.

Macrophage-restricted Interleukin-10 receptor-, but not IL-10 deficiency causes severe spontaneous colitis

(Submitter supplied) Interleukin-10 (IL-10) is a pleiotropic anti-inflammatory cytokine produced and sensed by most hematopoietic cells. Genome wide association studies and experimental animal models point at a central role of the IL-10 axis in Inflammatory Bowel Diseases. Here we investigated the importance of intestinal macrophage production of IL-10 and their IL-10 exposure, as well as the existence of an IL-10-based autocrine regulatory loop in the gut. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS5668
Platform:
GPL6246
7 Samples
Download data: CEL
Series
Accession:
GSE56444
ID:
200056444
2.
Full record GDS5668

Macrophage-restricted interleukin-10 receptor deficiency effect on colonic resident macrophages

Analysis of FACS-sorted, interleukin-10 receptor (IL-10R)-deficient intestinal macrophages from 6-week-old C57BL/6 animals. IL-10 is a pleiotropic anti-inflammatory cytokine. Results provide insight into the role of IL-10 sensing by intestinal macrophages in gut homeostasis.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL6246
Series:
GSE56444
5 Samples
Download data: CEL
DataSet
Accession:
GDS5668
ID:
5668
3.

[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site
Organism:
Mus musculus
143 DataSets
2504 Series
28 Related Platforms
30419 Samples
Download data
Platform
Accession:
GPL6246
ID:
100006246
4.

FACS sorted resident macrophages from the colons of 6 weeks old CX3CR1cre:IL10Raflox/flox mice_SJ67

Organism:
Mus musculus
Source name:
FACS sorted resident macrophages_CX3CR1cre:IL10Raflox/flox
Platform:
GPL6246
Series:
GSE56444
Dataset:
GDS5668
Download data: CEL
Sample
Accession:
GSM1361644
ID:
301361644
5.

FACS sorted resident macrophages from the colons of 6 weeks old CX3CR1cre:IL10Raflox/flox mice_SJ54

Organism:
Mus musculus
Source name:
FACS sorted resident macrophages_CX3CR1cre:IL10Raflox/flox
Platform:
GPL6246
Series:
GSE56444
Dataset:
GDS5668
Download data: CEL
Sample
Accession:
GSM1361643
ID:
301361643
6.

FACS sorted resident macrophages from the colons of 6 weeks old CX3CR1gfp/+ mice_SJ68

Organism:
Mus musculus
Source name:
FACS sorted resident macrophages_CX3CR1gfp/+
Platform:
GPL6246
Series:
GSE56444
Dataset:
GDS5668
Download data: CEL
Sample
Accession:
GSM1361642
ID:
301361642
7.

FACS sorted resident macrophages from the colons of 6 weeks old CX3CR1gfp/+ mice_SJ56

Organism:
Mus musculus
Source name:
FACS sorted resident macrophages_CX3CR1gfp/+
Platform:
GPL6246
Series:
GSE56444
Dataset:
GDS5668
Download data: CEL
Sample
Accession:
GSM1361641
ID:
301361641
8.

FACS sorted resident macrophages from the colons of 6 weeks old CX3CR1gfp/+ mice_SJ55

Organism:
Mus musculus
Source name:
FACS sorted resident macrophages_CX3CR1gfp/+
Platform:
GPL6246
Series:
GSE56444
Dataset:
GDS5668
Download data: CEL
Sample
Accession:
GSM1361640
ID:
301361640
9.

FACS sorted CX3CR1hi macrophages from the colons of 6 weeks old IL10-/- CX3CR1gfp/+ mice_SJ41

Organism:
Mus musculus
Source name:
FACS sorted CX3CR1hi macrophages_IL10-/- CX3CR1gfp/+
Platform:
GPL6246
Series:
GSE56444
Download data: CEL
Sample
Accession:
GSM1361639
ID:
301361639
10.

FACS sorted CX3CR1hi macrophages from the colons of 6 weeks old CX3CR1gfp/+ mice_SJ38

Organism:
Mus musculus
Source name:
FACS sorted CX3CR1hi macrophages_CX3CR1gfp/+
Platform:
GPL6246
Series:
GSE56444
Download data: CEL
Sample
Accession:
GSM1361638
ID:
301361638
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Supplemental Content

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