GSE197864[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2001978641.

Maladaptive Positive Feedback Production of ChREBPβ Drives Glucotoxic β-Cell Failure

(Submitter supplied) Purpose: Test the role of ChREBPbeta in pancreatic beta cells using tools that distinguish ChREBPalpha and ChREBPbeta and loss and gain of function experiments, confirming its role in glucose toxicity and finding mitigation strategies. Methods: INS-1 832/13 cells cultured in 2 mM or 11 mM glucose were transduced with adenoviruses expressing GFP as control or ChREBPbeta. After 48 h, RNA was isolated and amplified via the NuGEN Ovation RNA-Seq System V2 prior to RNA sequencing. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL18694
12 Samples

Download data: TXT

Series

Accession:: GSE197864

ID:: 200197864

Select item 1000186942.

Illumina HiSeq 2500 (Rattus norvegicus)

Organism:: Rattus norvegicus

495 Series
13319 Samples

Platform

Accession:: GPL18694

ID:: 100018694

Select item 3059314633.

ChREBPbeta 11 mM c

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931463

ID:: 305931463

SRA Run Selector

Select item 3059314624.

ChREBPbeta 11 mM b

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931462

ID:: 305931462

SRA Run Selector

Select item 3059314615.

ChREBPbeta 11 mM a

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931461

ID:: 305931461

SRA Run Selector

Select item 3059314606.

ChREBPbeta 2 mM c

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931460

ID:: 305931460

SRA Run Selector

Select item 3059314597.

ChREBPbeta 2 mM b

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931459

ID:: 305931459

SRA Run Selector

Select item 3059314588.

ChREBPbeta 2 mM a

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931458

ID:: 305931458

SRA Run Selector

Select item 3059314579.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931457

ID:: 305931457

SRA Run Selector

Select item 30593145610.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931456

ID:: 305931456

SRA Run Selector

Select item 30593145511.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931455

ID:: 305931455

SRA Run Selector

Select item 30593145412.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931454

ID:: 305931454

SRA Run Selector

Select item 30593145313.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931453

ID:: 305931453

SRA Run Selector

Select item 30593145214.

Organism:: Rattus norvegicus

Source name:: INS-1 832/13 cells

Platform:: GPL18694
Series:: GSE197864

Sample

Accession:: GSM5931452

ID:: 305931452

SRA Run Selector

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