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Items: 8

1.

Potent, p53-independent induction of NOXA sensitizes MLL-rearranged B-cell acute lymphoblastic leukemia cells to venetoclax [RNA-Seq]

(Submitter supplied) The prognosis for B cell precursor acute lymphoblastic leukemia patients with Mixed-Lineage Leukemia (MLL) gene rearrangements (MLLr BCP-ALL) is still extremely poor. Inhibition of anti-apoptotic protein BCL-2 with venetoclax emerged as a promising strategy for this subtype of BCP-ALL, however lack of sufficient responses in pre-clinical models and possibility of developing resistance exclude using venetoclax as monotherapy. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21697
6 Samples
Download data: TXT
Series
Accession:
GSE163227
ID:
200163227

PubMed Full text in PMC Similar studies Analyze with GEO2RSRA Run Selector

2.

NextSeq 550 (Homo sapiens)

Organism:
Homo sapiens
1499 Series
44577 Samples
Download data
Platform
Accession:
GPL21697
ID:
100021697

3.

RNA-seq in MLL-AF4 patient derived xenograft cells - VEN_3

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975378
ID:
304975378

SRA Run Selector

4.

RNA-seq in MLL-AF4 patient derived xenograft cells - VEN_2

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975377
ID:
304975377

SRA Run Selector

5.

RNA-seq in MLL-AF4 patient derived xenograft cells - VEN_1

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975376
ID:
304975376

SRA Run Selector

6.

RNA-seq in MLL-AF4 patient derived xenograft cells - control_3

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975375
ID:
304975375

SRA Run Selector

7.

RNA-seq in MLL-AF4 patient derived xenograft cells - control_2

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975374
ID:
304975374

SRA Run Selector

8.

RNA-seq in MLL-AF4 patient derived xenograft cells - control_1

Organism:
Homo sapiens
Source name:
MLL-AF4+ acute lymphoblastic leukemia, patient derived xenograft
Platform:
GPL21697
Series:
GSE163227 GSE163229
Download data
Sample
Accession:
GSM4975373
ID:
304975373

SRA Run Selector

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