GEO DataSets

(Submitter supplied) Copy number profiling of 27 gastric cancer cell lines and 105 gastric tumor tissues. we hypothesized that a detailed fine-scale survey of genomic CNAs might reveal potential genes disrupted by fusion events in gastric cancer. We inferred the locations of likely chromosomal breakpoints by identifying regions where closely-spaced microarray probes exhibited striking transitions in copy number.

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array

Platform:

GPL4544

132 Samples

Download data: TXT

(Submitter supplied) Mantle cell lymphoma is characterized by a t(11;14) chromosomal translocation; however, it alone is insufficient to result in the disease. A number of secondary genetic alterations have been proposed as essential in MCL pathogenesis. Amongst these, numerous copy number altered regions remain ill-defined, both for location and prognostic significance. In this study we examined in detail the genomes of a panel of 52 MCL cases. more...

Organism:

Homo sapiens

Type:

Expression profiling by SAGE; Genome variation profiling by array; Genome variation profiling by genome tiling array

Platforms:

GPL2616 GPL4544 GPL1485

57 Samples

Download data: TXT

(Submitter supplied) The association of genetic variation with disease and drug response, together with improvements in nucleic acids technologies, has given great optimism for the impact of 'genomic medicine'. However, the formidable size of the diploid human genome has prevented the routine application of sequencing methods to deciphering complete individual human genomes, and has so far limited the realization of the full potential of genomics for science and human health. more...

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array; Genome variation profiling by SNP array; SNP genotyping by SNP array

Platforms:

GPL3720 GPL4544 GPL3718

6 Samples

Download data: CEL, TXT

(Submitter supplied) This entry is part of a study comparing various array CGH platforms. In addition to the submitted data the following BT474 profiles were analyzed in this study: GSM69198 , GSM73557 and data from http://research.dfci.harvard.edu/meyersonlab/snp/snp.htm Keywords: Comparitive Genomic Hybridization (CGH) Platform Comparison

Organism:

Homo sapiens

Type:

Genome variation profiling by genome tiling array

Platform:

GPL4544

2 Samples

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(Submitter supplied) Alpha test array -- final design is Agilent-014693, P/N G4411B. Arrays of this design have barcodes that begin with 16014584 or 2514584. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...

Organism:

Homo sapiens

4 Series

138 Samples

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