GEO DataSets

(Submitter supplied) Chronic hypoxia (CH) produces changes not fully understood in morphology and function of the carotid body (CB). To characterize the effect of CH, primary rat CB cells were exposed to 7 days of CH, total RNA was extracted, cDNA-32P synthesized and hybridized with 1185 genes printed on a nylon membrane. Out of 324 differentially expressed genes, 184 were up-regulated and 140 were down-regulated. Since data analyses showed that nitric oxide synthases (NOS) and endothelin-1 (ET-1) pathways were enriched, we studied the effect of CH at protein levels of NOS isoforms and ET-1 receptors. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

2 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

56 Samples

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(Submitter supplied) CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 5 day of reloading

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

12 Samples

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(Submitter supplied) CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after 1 day of reloading

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

12 Samples

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(Submitter supplied) CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle after unloading

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

8 Samples

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(Submitter supplied) CMV-driven inhibition of FAK in soleus muscle was compared vs contralateral muscle

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

12 Samples

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(Submitter supplied) CMV-driven FAK overexpression in soleus muscle was compared vs empty transfection in contralateral muscle

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

12 Samples

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(Submitter supplied) The processes of adaptation to environmental heat and aerobic exercise training improve efficiency in various body systems and bring about acclimatory homeostasis. In order to examine the global genomic responses of the soleus and heart following exposure of rats to these stressors, nylon cDNA Atlas Array was used. Male rats were exposed to one of the following stressors: heat acclimation, aerobic training (treadmill), and combined heat acclimation and aerobic training for short (2, 3 days) and long (1 mo) time period. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

14 Samples

Download data: TXT

(Submitter supplied) The aim of this work was to determine if OE treatment affects the expression of genes that regulate lipid metabolism in white adipose tissue. Gene expression in adipose tissue from female treated rats (48 hours) was analysed by hybridization to cDNA arrays and levels of specific mRNAs were determined by Real-Time PCR. Treatment with OE decreased the expression of 232 genes and up-regulated 75 other genes in mesenteric white adipose tissue. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

4 Samples

Download data: TXT

(Submitter supplied) The effect of acetyl-L-carnitine (ALCAR) supplementation to hindlimb suspended rats has been analyzed in order to test whether this would promote the differentiation towards an oxidative phenotype of muscle fibers in soleus muscle and prevent the transformation of this slow tonic muscle towards a glycolytic, low-oxidative phenotype due to unloading condition. 3 month-old rats were daily supplemented with ALCAR concomitantly with hindlimb suspension. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

28 Samples

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

23 Samples

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(Submitter supplied) 1-day and 7-day sham and MI hearts Keywords = Heart Keywords = Mycardial infarction Keywords = 1 day post-MI Keywords = 7 day post-MI Keywords: parallel sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS2145

Platform:

GPL153

24 Samples

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Analysis of the heart left ventricle 1 or 7 days after ligation of the left anterior descending coronary artery to induce myocardial infarction (MI). Animals subjected to MI had congestive heart failure (CHF) on day 7. Results identify genes involved in the progression to CHF.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 2 disease state, 2 time sets

Platform:

GPL153

Series:

GSE1957

24 Samples

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(Submitter supplied) We studied the global genomic response in the hypothalamus during heat acclimation, with and without combined hypohydration stress. Rats were acclimated for 2 days or for 30 days at 34°C. Hypohydration (10% decrease in body weight) was attained by water deprivation. Functional analyses demonstrated a bi-phasic acclimatory profile with a transient upregulation of genes encoding ion channels, transporters, and transmitter signaling upon 2 days acclimation, suggesting enhanced neuronal excitability at that acclimation phase. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

6 Samples

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(Submitter supplied) Conditioned Taste Aversion experiment Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

1 Sample

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(Submitter supplied) 14 days hindlimb suspended, 5 days reloaded m. soleus RNA was isolated from cryosections using RNeasy kit (Qiagen). 5 microgram total RNA was subjected to microarray analysis. Keywords: time-course

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

5 Samples

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(Submitter supplied) heart from rats exposed to cardiopulmonary bypass (CPB) vs sham-operated controls Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platforms:

GPL153 GPL154

12 Samples

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(Submitter supplied) hearts from rats exposed to cardiopulmonary bypass (CPB) vs sham-operated controls Keywords = rat Keywords = heart Keywords = cytokine Keywords = inflammation Keywords: repeat sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

6 Samples

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(Submitter supplied) Examination of effect of mechanical loading induced by hindlimb suspension, and subsequent reloading, in soleus muscle in 14 day old female pathogen–free Wistar rats. Keywords = skeletal muscle Keywords = atrophy Keywords: other

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

18 Samples

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(Submitter supplied) 14 days suspended, 1 day reloaded Keywords: repeat sample

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Platform:

GPL153

6 Samples

Download data