GPL14613[RGSE] - GEO DataSets

(Submitter supplied) Morphogenesis of the mammalian neural tube (NT) is reliant on precise, spatio-temporal expression of numerous genes and coordinated interaction of signal transduction and gene regulatory networks, disruption of which may contribute to the etiology of neural tube defects (NTDs). MicroRNAs (miRNAs) as well as their downstream messenger RNA (mRNA) targets are key modulators of cell and tissue differentiation. more...

Organism:: Mus musculus; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
12 Samples

Download data: CEL

Series

Accession:: GSE140776

ID:: 200140776

Select item 2001832274.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
30 Samples

Download data: CEL

Series

Accession:: GSE183227

ID:: 200183227

Select item 2001832265.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and Unpaired Bone Marrow Donors

(Submitter supplied) Fanconi anemia (FA) is a rare genetic disorder characterized by genomic instability, developmental defects and bone marrow failure. Homeostasis of hematopoietic stem cells (HSCs) in the bone marrow partly relies on their direct or indirect interactions with the mesenchymal stem/stromal cells (MSCs). miRNAs can play a critical role during these interactions. There is no study available so far addressing the miRNA profile of bone marrow (BM-) MSCs in the FA disease state. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
9 Samples

Download data: CEL

Series

Accession:: GSE183226

ID:: 200183226

Select item 2001832256.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before and After Bone Marrow Transplantation, and their Allogeneic Bone Marrow Donors

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
9 Samples

Download data: CEL

Series

Accession:: GSE183225

ID:: 200183225

Select item 2001832247.

Global miRNA Expression of Bone Marrow Mesenchymal Stem/Stromal Cells in Fanconi Anemia Patients Before Transplantation and their Allogeneic Bone Marrow Donors

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
12 Samples

Download data: CEL

Series

Accession:: GSE183224

ID:: 200183224

Select item 2001966168.

MicroRNA expression data from LCMV infected CD8 T cells

(Submitter supplied) Investigating the role of microRNAs (miRs) in CD8 T cells responding to acutely resolved or chronic viral infection identified miR-29a as a key regulator of Tcell exhaustion cells We used miRNA microarrays to understand the role in development of T cell exhaustion in setting of LCMV infection

Organism:: Mus musculus; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
15 Samples

Download data: CEL

Series

Accession:: GSE196616

ID:: 200196616

Analyze with GEO2R

Select item 2001866669.

Expression data of microRNAs from human lung cancer at different clinical types

(Submitter supplied) Brain metastasis is a major complication of lung cancer. An investigation of the pathogenic mechanisms of brain metastasis, as well as the identification of appropriate molecular markers, is necessary. We used microarrays to determine the expression patterns of microRNAs in lung cancer tissue with or without brain metastasis and to investigate the biological role of these miRNAs during tumorigenesis.

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
45 Samples

Download data: CEL

Series

Accession:: GSE186666

ID:: 200186666

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20016763010.

Circulating non-coding RNAs in Huntington disease

(Submitter supplied) We performed a study of whole non-coding RNA expression profiles, by microarray, in plasma from 9 patients with Huntington disease (CH) in early stage and 13 controls: 8 healthy subjects (HD) and 5 patients with schizophrenia (SC). The CH patients were under antipsychotic drugs, the most effective treatment option also in SC patient (we included in the study SC control group to minimize the impact of neuroleptic drugson the expression of non-coding RNAs and to identify a HD-specific set of non-coding RNAs). more...

Organism:: synthetic construct; Homo sapiens

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
22 Samples

Download data: CEL

Series

Accession:: GSE167630

ID:: 200167630

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20016696111.

Detection of microRNAs in the plasma of cardiac surgery patients of high and low risk of developing non occlusive mesenteric ischemia

(Submitter supplied) Aim to identify circulating plasma miRNA markers of heart surgery and NOMI

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
30 Samples

Download data: CEL

Series

Accession:: GSE166961

ID:: 200166961

Analyze with GEO2R

Select item 20007715212.

Chorioamnion after choriodecidual Group B Streptococcal infection

(Submitter supplied) Choriodecidual infection is associated with preterm premature rupture of membranes (pPROM) and preterm birth. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression and may be involved in the pathway leading to chorioamnion weakening following infection. The study objective was to determine if a miRNA profile in the chorioamnion is associated with Group B Streptococcal infection and membrane weakening.

Organism:: Macaca nemestrina; synthetic construct

Type:: Expression profiling by array

Platform:: GPL14613
10 Samples

Download data: CEL

Series

Accession:: GSE77152

ID:: 200077152

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20014647713.

Microarray analysis of miRNA in breast cancer cell lines

(Submitter supplied) The project aimed to identify miRNA that varied with tumourigenicity in human breast cell lines. The second objective was to identify miRNA that had differential expression between cell lines that varied in accordance with the abundance of the tetraspanin CD9 in the cell lines and the degree to which endogenous factors within these cell lines interacted with the 3'UTR of CD9 as determined by dual luciferase assay. more...

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
6 Samples

Download data: CEL

Series

Accession:: GSE146477

ID:: 200146477

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20012139614.

miRNA expression in breast cancer cell lines

(Submitter supplied) We analyzed the miRNA expression in 6 breast cancer cell lines from young (HCC1500, HCC1937) and old (MCF-7, MDA-MB-231, HCC1806 and MDA-MB-468) patients with breast cancer using the GeneChip® miRNA 2.0 Array (Affymetrix, Santa Clara, CA, USA).

Organism:: Homo sapiens; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
18 Samples

Download data: CEL

Series

Accession:: GSE121396

ID:: 200121396

Analyze with GEO2R

Select item 20010364115.

Gene and microRNA expression data from mouse primary stomach tissues

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; synthetic construct

Type:: Expression profiling by array; Non-coding RNA profiling by array

Platforms:: GPL14613 GPL6246
15 Samples

Download data: CEL

Series

Accession:: GSE103641

ID:: 200103641

Select item 20010364016.

microRNA expression data from mouse primary stomach tissues

(Submitter supplied) We investigated microRNA expression profiles of gastric cancer tissues from Pdx-1-Cre;Cdh1F/+;Trp53F/F;Smad4F/F mice (pChePS_GC) and normal gastric epithelium (NGE) from Pdx1-1-Cre-negative mice. We used microarrays to detail the global microRNA expression underlying gastric carcinogenesis and identified distinct classes of up and down-regulated microRNAs during this process.

Organism:: Mus musculus; synthetic construct

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
4 Samples

Download data: CEL

Series

Accession:: GSE103640

ID:: 200103640

Select item 20013602017.

The miRNA Profile and Bioinformatic Analysis for Diagnosis in Patients with Stage IIIA Colon Cancer

(Submitter supplied) The aim of this study is to analyze microRNA expression profile, and through bioinformatic analyses determine the cellular processes of potential target genes and understand their molecular mechanism in stage IIIA colon cancer patients. The microRNA expression profiles of both normal and tumor tissues of seven patients were analyzed using the Affymetrix microarray system.

Organism:: Homo sapiens; synthetic construct

Type:: Expression profiling by array

Platform:: GPL14613
14 Samples

Download data: CEL, CHP

Series

Accession:: GSE136020

ID:: 200136020

Analyze with GEO2R

Select item 20010288318.

Expression data of miRNA from parental B16F0 cells and B16F0 exosomes [miRNA]

(Submitter supplied) As a type of secreted membrane vesicle, exosomes are emerging as an important mode of cell-to-cell communication. The objective of this study was to compare the abundance of mRNA and miRNA present in the parental B16F0 cell to mRNA and miRNA present in exosomes isolated from B16F0 conditioned media. Identifying local mechanisms of immunosuppression is a key barrier for expanding the clinical benefit of cancer immunotherapy. more...

Organism:: synthetic construct; Mus musculus

Type:: Non-coding RNA profiling by array

Platform:: GPL14613
8 Samples

Download data: CEL

Series

Accession:: GSE102883

ID:: 200102883

Analyze with GEO2R

Select item 20008510519.

miRNA Biomarker candidates fo the detection of endometrial atypical hyperplasia

(Submitter supplied) in the current study we identified a miRNAs signature able to discriminate between typical and atypical endometrial hyperplasia the identification of molecular marker that can differentiate between these two distinct pathological conditions is highly considered to be useful for the clinical management of the patients, owing to the fact that hyperplasia with atypical change is associated with higher risk of develop cancer.