GEO DataSets

(Submitter supplied) The classical bordetellae (Bordetella pertussis, B. parapertussis, and B. bronchiseptica) are obligate aerobes that use only oxygen as their terminal electron acceptor for electron transport-coupled oxidative phosphorylation. Therefore, access to oxygen is critical for these bacteria to survive. To better understand how B. bronchiseptica changes its gene regulation when faced with different levels of oxygen, we grew liquid cultures of B. more...

Organism:

Bordetella bronchiseptica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL34533

12 Samples

Download data: TSV

(Submitter supplied) A longitudinal multi-omics analysis was carried out over a 26-hour small-scale fermentation of B. pertussis. Fermentations were performed in batch mode and under culture conditions intended to mimic industrial processes.

Organism:

Bordetella pertussis Tohama I

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32624

21 Samples

Download data: XLSX

(Submitter supplied) Purpose: To filter genes that may contribute to introcellualr survival of B. bronchiseptica inside Dictyostelium discoideum, the genes that differently expressed when bacteria inside amoebae or in culture medium are selected as target genes.

Organism:

Bordetella bronchiseptica

Type:

Expression profiling by high throughput sequencing

Platform:

GPL31033

4 Samples

Download data: XLSX

(Submitter supplied) Transcriptome analysis of Bordetella hinzii isolates from chronic infection in a human host with interleukin-12 receptor deficiency

Organism:

Bordetella hinzii

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30482

228 Samples

Download data: TSV

(Submitter supplied) Bordetella pertussis has been shown to encode regulatory RNAs, yet the post-transcriptional regulatory circuits on which they act remain to be fully elucidated. We generated mutants lacking the endonucleases RNase III and RNase E and assessed their individual impact on the B. pertussis transcriptome. RNA-Seq analysis showed differential expression of ~25% of the B. pertussis transcriptome in each mutant with only 28% overlap between data sets. more...

Organism:

Bordetella pertussis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL29570

15 Samples

Download data: TXT

(Submitter supplied) Copper is both essential and toxic to living beings, which therefore tightly control its intracellular concentration. At the host-pathogen interface, copper is used by phagocytic cells to kill invading microorganisms. We investigated copper homeostasis in the whooping cough agent Bordetella pertussis, which lives in the human respiratory mucosa and has no environmental reservoir. B. pertussis has considerably streamlined copper homeostasis mechanisms relative to other Gram-negative bacteria. more...

Organism:

Bordetella bronchiseptica; Bordetella pertussis

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL27446 GPL28142

12 Samples

Download data: XLSX

(Submitter supplied) We examined the global transcription of B. pertussis in different strains and culture conditions

Organism:

Bordetella pertussis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL27446

6 Samples

Download data: XLSX

(Submitter supplied) We examined the BvgA fixation on the genome of B. pertussis in different strains and culture conditions

Organism:

Bordetella pertussis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL27446

7 Samples

Download data: XLSX

(Submitter supplied) Purpose: Within the past 20 years, outbreaks of whooping cough, caused by Bordetella pertussis, have led to respiratory disease and infant mortalities, despite good vaccination coverage. This is due at least in part to the introduction of a less effective acellular vaccine in the 1990’s. It is crucial then to understand the molecular basis of B. pertussis growth and infection. The two-component system BvgA/BvgS is the B. more...

Organism:

Bordetella pertussis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23369

8 Samples

Download data: XLSX

(Submitter supplied) We performed RNA-Seq transcriptomics analyses of the Bordetella holmesii type strain ATCC 51541T under in vitro growth conditions that mimic exposure to the human bloodstream. We sequenced 3 biological replicates of each of the following conditions of exposure to heat-inactivated human serum: 5% serum, 0.5% serum, and a no serum control.

Organism:

Bordetella holmesii

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18479

3 Samples

Download data: TXT