Serial Creatinine Clearance and 24-Hour Proteinuria Measurements During and After Pregnancy in Participants With Type 1 Diabetes, 1988–1994
| N | MEAN ± STANDARD DEVIATION | ||||
|---|---|---|---|---|---|
| Estimated Gestational Age (Weeks) | Follow-up* | ||||
| <20 | 20–28 | 28–38 | |||
| Change in Creatinine Clearance (mL/min) | |||||
| Initial creatinine clearance | |||||
| All persons | 45 | 120±53.1 | 112.2±46.1 | 105.3±47.1 | 77.9±45.4 |
| >90 mL/min | 34 | 139±45 | 130±37 | 119±44 | 94±43 |
| 60–90 mL/min | 7 | 76±8 | 80±15 | 81±21 | 68±27 |
| <60 mL/min | 4 | 35±12 | 34±6 | 33±18 | 14±8† |
| Change in Proteinuria (g/24 h) | |||||
| Initial collection | |||||
| All persons | 45 | 1.74±1.33 | 3.60±3.22 | 4.82±4.7 | 2.94±4.26 |
| <1 g/24 h | 20 | 0.68±0.23 | 1.44±1.34 | 2.05±1.51 | 0.82±0.59 |
| 1–3 g/24 h | 19 | 2.0±0.59 | 4.81±3.82 | 6.62±5.40 | 2.8±4.11 |
| >3 g/24 h | 6 | 4.44±0.78 | 5.58±1.73 | 8.93±4.52 | 6.71±5.90 |
Mean follow-up was 2.8±1.8 years. Follow-up information was obtained for 34 out of the 45 women.
Three persons with kidney transplant
From: Kidney Disease and Diabetes
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