TABLE 16

Results of regression analyses for costs and QALYs: subgroup analysis by age group

Age groupCoefficient95% CIp-valueMarginal effect
< 70 years (n = 1414) Total cost of hospital stay
Intervention arm−0.037−0.133 to 0.0580.441−668
Total cost for blood products
Intervention arm0.2830.160 to 0.406< 0.01543
Total cost
Intervention arm−0.006−0.092 to 0.0790.866−124
QALYs (without imputation) a
Intervention arm0.0003−0.002 to 0.0010.752
QALYs (with imputation)
Intervention arm−0.001−0.002 to 0.0010.247
≥ 70 years (n = 167) Total cost of hospital stay
Intervention arm0.143−0.188 to 0.4730.3972007
Total cost for blood products
Intervention arm0.156−0.128 to 0.4410.281236
Total cost
Intervention arm0.144−0.164 to 0.4510.3592242
QALYs (without imputation) b
Intervention arm−0.0003−0.003 to 0.0020.848
QALYs (with imputation)
Intervention arm0.0004−0.003 to 0.0030.819
a

n = 932.

b

n = 129.

From: Chapter 4, Economic evaluation

Cover of Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis
Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis.
Health Technology Assessment, No. 28.76.
Curry N, Davenport R, Thomas H, et al.
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