TABLE 15, [Results of regression analyses for costs and QALYs: subgroup analysis by injury type]. - Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis

Ιnjury type		Coefficient	95% CI	p-value	Marginal effect
Blunt (n = 1014)	Total cost of hospital stay
Intervention arm	0.015	0.089 to 0.119	0.779	308
Total cost for blood products
Intervention arm	0.178	0.034 to 0.322	0.015	325
Total cost
Intervention arm	0.028	−0.067 to 0.123	0.560	633
QALYs (without imputation) ^a
Intervention arm	0.006	−0.001 to 0.002	0.498
QALYs (with imputation)
Intervention arm	0.003	−0.001 to 0.002	0.676
Penetrating (n = 567)	Total cost of hospital stay
Intervention arm	−0.075	−0.116 to 0.098	0.866	−874
Total cost for blood products
Intervention arm	0.437	0.254 to 0.620	< 0.01	857
Total cost
Intervention arm	−0.001	−0.168 to 0.166	0.988	−17
QALYs (without imputation) ^b
Intervention arm	−0.003	−0.006 to 0.000	0.082
QALYs (with imputation)
Intervention arm	−0.003	−0.005 to −0.001	0.023

Cover of Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis

Early high-dose cryoprecipitate to reduce mortality in adult patients with traumatic haemorrhage: the CRYOSTAT-2 RCT with cost-effectiveness analysis.

Health Technology Assessment, No. 28.76.

Curry N, Davenport R, Thomas H, et al.

Southampton (UK): National Institute for Health and Care Research; 2024 Nov.

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