Table 27, EHR Medication-Naive Database Cox Regression HRs for Demographic and Treatment Regimen Variables for Reaching HbA1c Target <7.0% (N = 8107), All Other Medications vs Metformin - Benchmarking the Comparative Effectiveness of Diabetes Treatments Using Patient-Reported Outcomes and Socio-Demographic Factors

Patient characteristic	β coefficient (B)	SE	Wald	df	P value	HR Exp(B)	95% CI for Exp(B)
Age, y	.006	0.001	27.301	1	.000	1.006	1.004-1.009
Female vs male	.133	0.026	26.625	1	.000	1.142	1.086-1.201
BMI	.003	0.002	2.495	1	.114	1.003	0.999-1.007
Hypertension	−.068	0.028	5.738	1	.017	0.934	0.884-0.988
eGFR	−.001	0.001	4.971	1	.026	0.999	0.997-1.000
Race (vs White)			7.062	4	.133
Black	−.042	0.039	1.175	1	.278	0.959	0.888-1.035
Asian	.093	0.068	1.872	1	.171	1.098	0.960-1.255
Hispanic	−.021	0.046	0.199	1	.655	0.980	0.895-1.072
Other	−.089	0.046	3.737	1	.053	0.915	0.835-1.001
Baseline HbA_1c	−.064	0.008	68.370	1	.000	0.938	0.924-0.952
All other medications vs metformin	−.490	0.029	285.856	1	.000	0.613	0.579-0.648

Patient characteristic

β coefficient (B)

Wald

P value

HR Exp(B)

95% CI for Exp(B)

Age, y

.006

0.001

27.301

.000

1.006

1.004-1.009

Female vs male

.133

0.026

26.625

.000

1.142

1.086-1.201

BMI

.003

0.002

2.495

.114

1.003

0.999-1.007

Hypertension

−.068

0.028

5.738

.017

0.934

0.884-0.988

eGFR

−.001

0.001

4.971

.026

0.999

0.997-1.000

Race (vs White)

7.062

.133

Black

−.042

0.039

1.175

.278

0.959

0.888-1.035

Asian

.093

0.068

1.872

.171

1.098

0.960-1.255

Hispanic

−.021

0.046

0.199

.655

0.980

0.895-1.072

Other

−.089

0.046

3.737

.053

0.915

0.835-1.001

Baseline HbA_1c

−.064

0.008

68.370

.000

0.938

0.924-0.952

All other medications vs metformin

−.490

0.029

285.856

.000

0.613

0.579-0.648

From: Benchmarking the Comparative Effectiveness of Diabetes Treatments Using Patient-Reported Outcomes and Socio-Demographic Factors

Cover of Benchmarking the Comparative Effectiveness of Diabetes Treatments Using Patient-Reported Outcomes and Socio-Demographic Factors

Benchmarking the Comparative Effectiveness of Diabetes Treatments Using Patient-Reported Outcomes and Socio-Demographic Factors [Internet].

Testa MA, Su M, Turchin A, et al.

Washington (DC): Patient-Centered Outcomes Research Institute (PCORI); 2021 Mar.

This book is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License which permits noncommercial use and distribution provided the original author(s) and source are credited. (See https://creativecommons.org/licenses/by-nc-nd/4.0/

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Table 27EHR Medication-Naive Database Cox Regression HRs for Demographic and Treatment Regimen Variables for Reaching HbA1c Target <7.0% (N = 8107), All Other Medications vs Metformin

Table 27EHR Medication-Naive Database Cox Regression HRs for Demographic and Treatment Regimen Variables for Reaching HbA_1c Target <7.0% (N = 8107), All Other Medications vs Metformin