Table 17Marginal Time and Treatment Effects for Claims-based Secondary Outcome Measures

OutcomesICC: clinics, participantsChange over time from baselineLeast-squares estimates (95% CI)Change by treatment from baselineLeast-squares estimates (95% CI)
F value (df)P valueF value (df)P valuePSSD
Medication adherence: MPR for antipsychotics  0.000, 0.5302.30 (4, 996).0569--0.82 (1, 9).39000.75 (0.61-0.89)0.73 (0.57-0.88)
 mo 0----0.75 (0.62-0.87)--------
 mo 6----0.74 (0.61-0.87)--------
 mo 12----0.75 (0.65-0.86)--------
 mo 18----0.70 (0.56-0.85)--------
 mo 24----0.75 (0.61-0.88)--------
Medication adherence: MPR for antidepressants  0.003, 0.5791.58 (4, 1254).1772--4.41 (1, 9).06510.81 (0.74-0.89)0.77 (0.67-0.87)
 mo 0----0.79 (0.72-0.86)--------
 mo 6----0.78 (0.70-0.87)--------
 mo 12----0.81 (0.73-0.88)--------
 mo 18----0.78 (0.69-0.88)--------
 mo 24----0.79 (0.73-0.86)--------
Medication adherence: MPR for hypertension 0.000, 0.48522.40 (4, 656)< .0001a--2.83 (1, 9).12670.71 (0.58-0.85)0.68 (0.52-0.84)
 mo 0----0.66 (0.52-0.79)--------
 mo 6----0.68 (0.55-0.81)--------
 mo 12----0.71 (0.57-0.86)--------
 mo 18----0.72 (0.59-0.85)--------
 mo 24----0.71 (0.60-0.83)--------
Laboratory monitoring: EKG services in 12 mo 0.000, 0.1880.03 (2, 2144).9696--3.44 (1, 9).09660.13 (0.05-0.22)0.11 (0.01-0.20)
 mo 0----0.12 (0.05-0.19)--------
 mo 12----0.12 (0.06-0.19)--------
 mo 24----0.12 (0.01-0.23)--------
Laboratory monitoring: Lipid labs services in 12 mo 0.027, 0.4407.86 (2, 2144).0004a--2.08 (1, 9).18310.42 (0.09-0.75)0.29 (0.08-0.50)
 mo 0----0.31 (0.08-0.54)--------
 mo 12----0.36 (0.14-0.59)--------
 mo 24----0.39 (0.17-0.61)--------

Abbreviations: ICC, integrated comprehensive care; EKG, electrocardiogram; MPR, medication possession ratio; PS, provider-supported intervention arm; SD, self-directed intervention arm.

aSignificant at P < .05.

From: Using Wellness Coaches and Extra Support to Improve the Health and Wellness of Adults with Serious Mental Illness

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Using Wellness Coaches and Extra Support to Improve the Health and Wellness of Adults with Serious Mental Illness [Internet].
Schuster J, Reynolds C III, Carney T, et al.
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