Table 3:

Allele Frequencies of Common CYP2D6 Alleles from TOPMed Studies

Country/ ancestry*2*3*4*5*6*9*10*17*29*41Ref
European14.811.5713.803.081.062.541.580.160.079.83(21)
African16.110.353.635.670.260.533.8315.718.402.40(21)
Hispanic/Latino16.480.869.552.960.551.461.651.721.245.72(21)
Asian9.530.516.2412.880.0364.02(21)
Samoan17.200.050.161.300.101.510.315.41(21)
Amish9.338.445.114.897.33(21)

The alleles shown are commonly observed across populations and correspond to those designated by AMP as Tier 1 in their clinical allele testing recommendations (17).

Allele frequencies are given as percentages (%).

Blank values indicate that no frequency was given for that allele from the cited study.

From: CYP2D6 Overview: Allele and Phenotype Frequencies

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