Table 1.

The FDA Drug Label for Dronabinol. Effect of CYP2C9 Polymorphism (2020)

PhenotypeRecommendations
CYP2C9 poor metabolizerPublished data suggest that systemic clearance of dronabinol may be reduced and concentrations may be increased in the presence of CYP2C9 genetic polymorphism. Monitoring for potentially increased adverse reactions is recommended in individuals known to have genetic variants associated with diminished CYP2C9 function.

This table is adapted from (1).

From: Dronabinol Therapy and CYP2C9 Genotype

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