[Table, Question in PICO format]. - Neutropenic Sepsis: Prevention and Management of Neutropenic Sepsis in Cancer Patients

Patients/population	Intervention	Comparison	Outcomes
Patients with central venous access devices and neutropenia or neutropenic sepsis, without an identified bacterium.	Empiric vancomycin, teicoplanin, linezolid in addition to first line antibiotics	First-line, broad spectrum antibiotics	Death critical care, Length of stay Line preservation / “catheter remains in situ” Antibiotic resistance Proven Bacteraemia Toxicity

Neutropenic Sepsis: Prevention and Management of Neutropenic Sepsis in Cancer Patients.

NICE Clinical Guidelines, No. 151.

National Collaborating Centre for Cancer (UK).

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