| Quality assessment | No of patients | Effect | Quality | Importance | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other | Nutritional supplement and standard hospital diet | Standard hospital diet | Relative (95% CI) | Absolute | ||
| PUSH scores at week 3 (0=complete healing, 17=greatest severity) (final scores) – elderly adults or people with a spinal injury, stage 2, 3 or 4 ulcersd (unclear if nutritionally deficient)54 | ||||||||||||
| 1 | Randomised trial | Very seriousa | No serious inconsistency | No serious indirectness | Very seriousb | Seriousc | 6 (s.d 1.2) n=5 | 7 (s.d 1.5) n=6 | - | MD 1 lower (2.6 lower to 0.6 higher) | Very low | Critical |
| Proportion of people with pressure ulcers completely healed | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Time to complete healing of pressure ulcers | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Reduction in size or volume of pressure ulcers | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Rate of change in size or volume of pressure ulcers | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Pain (wound-related) | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | ||
| Time in hospital | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Patient acceptability | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Side effects (nausea, vomiting, diarrhoea) | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Mortality (all-cause) | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
| Health-related quality of life | ||||||||||||
| - | - | - | - | - | - | - | - | - | - | - | - | - |
Desneves (2005)54 :did not provide details of allocation concealment or details of blinding of participants or those administering treatment. However, outcome assessors were blinded.
The confidence interval crossed both MID points (0.75 to 1.25 for dichotomous data and 0.5 × SD for continuous data).
The between-group comparisons were evaluated using the Mann-Whitney U-test but no log transformations conducted.
Australian Wound Management Association Clinical Practice Guidelines classification of pressure ulcers.
From: 5, Nutrition and hydration
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